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MetabolomicsOral dysbiosis initiates periodontal disease in experimental kidney disease

BACKGROUND AND HYPOTHESIS: It is presently unclear why there is a high prevalence of periodontal disease in individuals living with chronic kidney disease. Whilst some have argued that periodontal disease causes chronic kidney disease, we hypothesized that alterations in saliva ...

2025-09-04 | MTBLS1833 | MetaboLights
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
ProteomicsThe ubiquitin ligase UBR5 suppresses proteostasis collapse in immortal pluripotent stem cells and Huntington’s disease models
Pluripotent stem cells undergo unlimited self-renewal while maintaining their potential to differentiate into post-mitotic cells with an intact proteome, a capacity that demands a highly induced proteostasis network. As such, induced pluripotent stem cells (iPSCs) suppress the aggregation of polyQ-e...
ORGANISM(S): Homo sapiens (Human) 
2018-06-14 | PXD009803 | Pride
Human cells (293) Htt 
UnknownSpatial Localization of Vitamin D Metabolites in Mouse Kidney by Mass Spectrometry Imaging.
Not available
S-EPMC7288721 | biostudies-literature
UnknownCalcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial.
Not available
S-EPMC3157967 | biostudies-literature
GenomicsORC2 S2-DSRC ChIP-Seq experiment
modENCODE_submission_2753 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known ...
ORGANISM(S): Drosophila melanogaster 
2010-03-16 | E-GEOD-20887 | biostudies-arrayexpress
TranscriptomicsTranscription start site identification in Bacillus subtilis
Cappable-seq was used to map transcription start sites globally in wild type Bacillus subtilis. Total RNA was isolated from cells grown in LB media until exponential phase. RNA corresponding to transcription start sites was capped with a 5' biotin tag, which was used for enrichment via a pull down w...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2021-04-16 | E-MTAB-8582 | biostudies-arrayexpress
GenomicsORC2 ML-DmBG3-c2 ChIP-Seq experiment
modENCODE_submission_2754 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known ...
ORGANISM(S): Drosophila melanogaster 
2010-03-16 | E-GEOD-20888 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 10 sample types: normal colon tissue, non cancerous adenomas, Dukes B carcinomas, Dukes C carcinomas, Dukes D carcinomas, and liver metastases, see also E-TIGR-14, E-TIGR-15
This study was designed to find patterns of gene expression in colon cancer samples that correlate with clinical stage. Ten samples were profiled from each of the following sample types: normal colon tissue, noncancerous adenomas, Dukes B carcinomas, Dukes C carcinomas, Dukes D carcinomas, and liver...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-TIGR-14 | biostudies-arrayexpress
Genomics24 Hour ORC ChIP-Seq experiment
modENCODE_submission_3247 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We will precisely identify sequence elements that direct DNA replication by using chromatin immunoprecipitation of known ...
ORGANISM(S): Drosophila melanogaster 
2011-03-23 | E-GEOD-28067 | biostudies-arrayexpress
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