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TranscriptomicsGenome-wide analysis of c-Myb-responsive gene expression in prostate cancer cells
Analysis of c-Myb-regulation of gene expression. The hypothesis tested in the present study was that c-Myb influences the expression of specific sets of genes that are involved in cell cycle, DNA replication, recombination and repair. Results provide important information on c-Myb-responsive genes ...
ORGANISM(S): Homo sapiens 
2013-07-28 | E-GEOD-49286 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of AR-responsive gene expression in prostate cancer cells
Analysis of AR-regulation of gene expression. The hypothesis tested in the present study was that AR influences the expression of genes that participate in important bioprocesses in prostate cancer cells, including cell cycle, DNA replication, recombination and repair. Results provide important in...
ORGANISM(S): Homo sapiens 
2013-07-28 | E-GEOD-49285 | biostudies-arrayexpress
TranscriptomicsTissue Transcriptome Driven Identification of Epidermal Growth Factor as a Chronic Kidney Disease Biomarker
We identified EGF as the top candidates predicting kidney function through an intrarenal transcriptome-driven approach, and demonstrated it is an independent risk predictor of CKD progression and can significantly improve prediction of renal outcome by established clinical parameters in diverse popu...
ORGANISM(S): Homo sapiens 
2015-12-14 | E-GEOD-69438 | biostudies-arrayexpress
TranscriptomicsIn silico nano-dissection: defining cell type specificity at transcriptional level in human disease (glomeruli)
To identify genes with cell-lineage-specific expression not accessible by experimental micro-dissection, we developed a genome-scale iterative method, in-silico nano-dissection, which leverages high-throughput functional-genomics data from tissue homogenates using a machine-learning framework. This ...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-47183 | biostudies-arrayexpress
TranscriptomicsIn silico nano-dissection: defining cell type specificity at transcriptional level in human disease (tubulointerstitium)
To identify genes with cell-lineage-specific expression not accessible by experimental micro-dissection, we developed a genome-scale iterative method, in-silico nano-dissection, which leverages high-throughput functional-genomics data from tissue homogenates using a machine-learning framework. This ...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-47184 | biostudies-arrayexpress
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