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ProteomicsDeuterium-free, Three-plexed Peptide Di-Ethylation for Highly Accurate Quantitative Proteomics
The deuterium, frequently used stable isotope in isotopic labeling for quantitative proteomics, could deteriorate the accuracy and precision of proteome quantification owing to the retention time shift of deuterated peptides from the hydrogenated counterpart. Herein, we introduce a novel three-plexe...
ORGANISM(S): Homo sapiens (Human) 
2019-01-17 | PXD012117 | Pride
Isobaric labeling Quantitative accuracy Di-methylation Isotopic labeling Deuterium effect Di-ethylation 
ProteomicsHuman synovial fluid proteomics reveals potential early-diagnostic biomarkers for ankylosing spondylitis
[Background] Ankylosing spondylitis (AS), affecting 0.5% of the population, is a chronic inflammatory rheumatic disease affecting the axial skeleton and peripheral joints. The etiology of this disease is still poorly understood, but it may be involved with the interaction of genetic and environmen...
ORGANISM(S): Homo sapiens (Human) 
2021-07-15 | PXD016620 | Pride
Synovial fluid Proteomics Biomarker Ankylosing spondylitis 
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