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UnknownImplementation of a diabetes prevention program within two community sites: a qualitative assessment.
Not available
S-EPMC8817168 | biostudies-literature
TranscriptomicsTranscription profiling by array of human jurkat cells after mitogen stimulation
Gene expression analysis identified 27 of these 744 p300 and pol II associated genes as significantly increased (p? 0.05) within the first hour following mitogen stimulation Experiment Overall Design: Total RNA was purified from Jurkat T-cells treated 0, 30, and 60 min with phorbol ester and ionomyc...
ORGANISM(S): Homo sapiens 
2009-12-11 | E-GEOD-11118 | biostudies-arrayexpress
TranscriptomicsStem cell factor programs the mast cell activation phenotype
Mast cells, activated by antigen via the high affinity receptor for IgE (FcεRI), release an array of pro-inflammatory mediators that contribute to allergic disorders such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation and survi...
ORGANISM(S): Mus musculus 
2012-05-01 | E-GEOD-35332 | biostudies-arrayexpress
TranscriptomicsIL-33 induces a hypo-responsive human mast cell phenotype
Interleukin-33 (IL-33) is elevated in afflicted tissues of patients with mast cell-dependent chronic allergic diseases. Based on its acute effects on mouse mast cells (MCs), IL-33 is thought to play a role in the pathogenesis of allergic disease through MC activation. However, the manifestations of ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-39382 | biostudies-arrayexpress
TranscriptomicsStem cell factor Sox2 regulates the tumorigenic potential in human gastric cancer cells
Gastric cancer is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with H. pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-42937 | biostudies-arrayexpress
UnknownSclerotic prostate cancer bone metastasis: woven bone lesions with a twist.
Not available
S-EPMC11365963 | biostudies-literature
TranscriptomicsscRNA-seq study of hippocampal microglia, perivascular macrophages and perivascular fibroblasts in pre-plaque APP-KI mice
Aim of this experiment was to characterize whether SPP1 released from the hippocampal perivascular space could imprint microglia transcriptional states. We performed scRNA-seq analysis on sorted CD140a+ perivascular fibroblast (PVF), CD45highCD11intCD206+ perivascular macrophage (PVM) and CD45intCD1...
ORGANISM(S): Mus musculus 
2024-02-09 | E-MTAB-11918 | biostudies-arrayexpress
TranscriptomicsCell-type specific phenotypic characterization of Lyve1+ perivascular macrophages and Sall1+ microglia pooled from PBS and amyloid-β-injected mice
RiboTag-based translatome analysis of pooled oAβ and PBS-challenged brain homogenates of Cx3cr1ccre:Lyve1ncre (n=8 mice) and Cx3cr1ccreSall1ncre:RiboTag-mice (n=4 mice).
ORGANISM(S): Mus musculus 
2023-01-10 | E-MTAB-12515 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae treated with Small Molecule Enhancers of Rapamycin (SMERs)
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-29 | E-GEOD-22269 | biostudies-arrayexpress
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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