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TranscriptomicsThe nuclear pore-associated TREX-2 complex employs the Mediator Med31 submodule as a docking site to regulate gene expression
Nuclear pore complexes (NPCs) influence gene expression besides their established function in nuclear transport. The TREX-2 complex localizes to the NPC basket and affects gene-NPC interactions, transcription and mRNA export. How TREX-2 regulates the gene expression machinery is unknown. Here, we sh...
ORGANISM(S): Saccharomyces cerevisiae 
2015-08-27 | E-GEOD-67431 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of brain and spinal cord of mice where Cip2a locus has been disrupted and wild-type control mice at the peak of Experimental Autoimmune Encephalomyelis
We induced Experimental Autoimmune Encephalomyelis (EAE) in mice carrying a gene-trap disruption of Cip2a (hereafter referred to as knockout [KO] mice) and wild-type (WT) control C57BL/6J male and female mice, aged 8-12 weeks. We performed scRNA-seq analysis of central nervous system (CNS), i.e., br...
ORGANISM(S): Mus musculus 
2026-10-15 | E-MTAB-17720 | biostudies-arrayexpress
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