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ATAC-seq of SLTM knockdown in HIV infected Jurkats
Although chimeric antigen receptor (CAR) T cell therapy has revolutionised individualised cancer therapies for relapsed/refractory lymphomas, low long-term retention due to basal signalling (antigen-independent activation in the absence of cognate antigen) and off-target toxicity limit the broad app...
ORGANISM(S): Homo sapiens (Human) 
2025-11-21 | PXD065669 | Pride
Transcriptomic impacts of TFIIB D207G editing in Jurkats during 2 h TRAIL treatment
Transcriptomic impacts of TFIIB D207G editing in Jurkats during 6 h TRAIL treatment
Determine melting temperature of proteins in Jurkats
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008639 | Pride
All bulk CRISPR based screens CD2 and B2M CRISPRi tiling screens (primary human CD8 T cells), IL2RA CRISPRa tiling screens (Jurkats), CRISPRi/a TF screens (primary human CD8 T cells), and CRISPR TFome KO (primary human T cells)
ORGANISM(S): Homo sapiens 
2023-08-31 | GSE241933 | GEO
In order to identify novel factors associated with regulation of HIV-1 transcription, we completed a genome-wide CRISPRi screen in a monogenic model of HIV-1. We identified SLTM mediated suppression of HIV-1 transcription. We hypothesized that SLTM would alter the chromatin acessibility at the site ...
ORGANISM(S): Homo sapiens 
2022-05-20 | GSE203235 | GEO
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