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MetabolomicsMetabolic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis
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ORGANISM(S): Homo sapiens 
ST001815 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of peripheral blood samples from juvenile idiopathic arthritis (JIA) patients pre and post methotrexate therapy. Expression data from SPARKS CHARMS JIA cohort
Gene expression on peripheral blood mononuclear cells (PBMC) from SPARKS CHARMS juvenile idiopathic arthritis (JIA) cohort pre and post methotrexate therapy. This is the first study to our knowledge, to evaluate gene expression profiles in children with JIA before and after MTX, and to analyze genet...
ORGANISM(S): Homo sapiens 
2010-09-27 | E-GEOD-23687 | biostudies-arrayexpress
TranscriptomicsBlood Leukocyte Microarrays to Diagnose Systemic Onset Juvenile Idiopathic Arthritis and Follow IL-1 blocade
Systemic onset Juvenile Idiopathic Arthritis (SoJIA) represents up to 20% of Juvenile Idiopathic Arthritis (JIA). We have previously reported that this disease is Interleukin 1 (IL1)-mediated, and that IL-1 blockade results in clinical remission in the majority of patients. The diagnosis of SoJIA, h...
ORGANISM(S): Homo sapiens 
2007-09-01 | E-GEOD-8650 | biostudies-arrayexpress
ProteomicssJIA serum proteome profiling with DIA-MS
We performed a DIA-MS proteomic analysis of sera from systemic juvenile idiopathic arthritis with different activity phases using a high protein depletion process. We profiled the proteins in the sera that differed significantly in their activity phase.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD030413 | JPOST Repository
TranscriptomicsRemission in Polyarticular Juvenile Idiopathic Arthritis
Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...
ORGANISM(S): Homo sapiens 
2009-04-13 | E-GEOD-15645 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peripheral blood monocytes from patients with systemic juvenile idiopathic arthritis during active and inactive disease
Comaprison of PBMCs from patients with systemic juvenile idiopathic arthritis during active and inactive disease
ORGANISM(S): Homo sapiens 
2007-03-31 | E-MEXP-987 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling in Peripheral Blood in Untreated New Onset Systemic Juvenile Idiopathic Arthritis
Systemic Juvenile Idiopathic Arthritis (sJIA) has been strongly associated with macrophage activation syndrome (MAS). To better understand the pathogenesid of sJIA and to facilitate the search for MAS biomarkers, we examine gene expression profiles in untreated new onset sJIA. 17 new onset sJIA pat...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-7753 | biostudies-arrayexpress
ProteomicsProteomic analysis of synovial fibroblasts from patients with Juvenile idiopathic arthritis
The aim was to characterize the proteomic alterations in synovial fibroblasts from patients with juvenile idiopathic arthritis, with or without prior priming with inflamed synovial fluid. Synovial fibroblasts were isolated from the synovial fluid of patients with oligoarticular juvenile idiopathic a...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD041459 | Pride
Synovial fluid Inflammation Juvenile idiopathic arthritis Synovial fibroblasts 
TranscriptomicsGene expression predictors of extension in oligoarticular juvenile idiopathic arthritis (JIA)
Children with oligoarticular JIA (arthritis in 4 or fewer joints) can either continue to have this mild form of arthritis (persistent oligoarticular JIA) or extend to a more sever form involving more than 4 joints (extended oligoarticular JIA) Synovial fluid mononuclear cell RNA was prepared from 21...
ORGANISM(S): Homo sapiens 
2009-03-04 | E-GEOD-15083 | biostudies-arrayexpress
TranscriptomicsJuvenile idiopathic arthritis: peripheral blood cells
Systemic-onset juvenile idiopathic arthritis (soJIA) is a rheumatic disease in childhood characterized by systemic symptoms and a relatively poor prognosis. The peripheral leukocytes are thought to play the pathological role of soJIA although the exact cause is still obscure. In this study, we aimed...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8361 | biostudies-arrayexpress
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