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ProteomicsBrain death associated activation of Calpain-Talin axis in donor kidneys underlies podocyte matrix degradation and graft dysfunction in kidney transplantation
Deceased kidney donation after brain death (DBD) is the main source of transplants, yet these grafts yield inferior transplant outcomes when compared to living donation. In brain death, cerebral injury contributes to systemic biological dysregulation, causing significant cellular stress in donor kid...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD022074 | Pride
Kidney cytoskeleton Podocytes Donation after brain death (dbd) Protein degradation Allograft dysfunction Kidney transplantation 
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