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TranscriptomicsTranscription profiling of human mammary epithelial cells with MycER activation using 4-hydroxytamoxifen following growth in 2D monoloyers with or without EGF and insulin or in 3D Matrigel culture
MCF10A MycER cells were grown either on 2D monolayer culture in the presence of complete growth medium, in the absence of EGF and insulin or in 3D Matrigel culture for 20 days to form acinar structures. MycER was activated with 4-hydroxytamoxifen (4-OHT) in all samples for 2 or 48 h. Control cells w...
ORGANISM(S): Homo sapiens 
2006-12-31 | E-MEXP-765 | biostudies-arrayexpress
UnknownChemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells.
Not available
S-EPMC3520796 | biostudies-literature
UnknownAnalysis of kinase gene expression patterns across 5681 human tissue samples reveals functional genomic taxonomy of the kinome.
Not available
S-EPMC2997066 | biostudies-literature
UnknownPLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells.
Not available
S-EPMC5402179 | biostudies-literature
TranscriptomicsThe effect of ERG overexpression and ERG knockdown by shRNA in RWPE1 and VCAP cells, respectively
The goal of this project was to analyze the global gene expression profiles of RWPE1 and VCAP cells following transfection of GFP, GFP-ERG at 48 and 72hrs time points and stable ERG shRNA, scramble shRNA, respectively. RWPE1 cells were transfected with GFP or GFP-ERG. VCAP cells were transfected wit...
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-16671 | biostudies-arrayexpress
UnknownClinical relevance of integrin alpha 4 in gastrointestinal stromal tumours.
Not available
S-EPMC5867167 | biostudies-literature
TranscriptomicsData integration from two microarray platforms identifies genetic inactivation of RIC8A in a breast cancer cell line
Using array comparative genomic hybridization (aCGH), a large number of deleted genomic regions have been identified in human cancers. However, subsequent efforts to identify target genes selected for inactivation in these regions have often been challenging. We integrated here genome-wide copy numb...
ORGANISM(S): Homo sapiens 
2010-06-19 | E-GEOD-15477 | biostudies-arrayexpress
UnknownHigh-resolution genomic and expression profiling reveals 105 putative amplification target genes in pancreatic cancer.
Not available
S-EPMC1550328 | biostudies-literature
UnknownThe gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition.
Not available
S-EPMC3680939 | biostudies-literature
UnknownReanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms.
Not available
S-EPMC3485361 | biostudies-literature
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