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double transgenic mice (tTA/IkappaBalpha-AA) were treated with doxycycline (DOX), which represses expression of the transgenic IkappaBalpha. Double transgenic mice without Dox-treatment overexpress the transdominant IkappaBalpha, which represses NFkappaB activation.
ORGANISM(S): Mus musculus 
Investigation of the alterations in the gene expression pattern of peripheral blood monocytes after constitutive adhesion to naive human umbilical vein endothelial cells
ORGANISM(S): Homo sapiens 
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