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Metabolomics4-Octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING

The Krebs cycle-derived metabolite itaconate, whose production is catalyzed by immune response gene 1 (IRG1), has excellent potential to link immunity and metabolism in activated macrophages through alkylation or competitive inhibition of target proteins. In support of this, our previous study de...

2023-01-15 | MTBLS5877 | MetaboLights
ProteomicsEffects of 3D printing HUVEC(vefg165+) -laden hydrogel on diabetic wound healing
By constructing specific lentiviral vector, vefg165 protein was overexpressed in HUVEC cells. Using light-curing bioprinting, HUVEC(vefg165+)-loaded hydrogels and HUVEC(vector)-loaded hydrogels were prepared, and were used to treat rat diabetic wounds. The regenerated skin tissues (five samples for ...
ORGANISM(S): Rattus Norvegicus 
2022-08-12 | PXD036045 |
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