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ProteomicsiTARGEX analysis of yeast deletome reveals novel regulators of transcriptional buffering in S phase and protein turnover
Integrating omics data with quantification of biological traits provides unparalleled opportunities for discovery of genetic regulators by in silico inference. However, current approaches to analyze genetic-perturbation screens are limited by their reliance on annotation libraries for prioritization...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-10 | PXD024258 | Pride
Itargex Protein turnover Transcriptional buffering 
TranscriptomicsGenome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-26 | E-GEOD-2994 | biostudies-arrayexpress
ProteomicsSilver binding proteins in S. aureus
The rapid emergence of drug resistant Staphylococcus aureus (S. aureus), in particular, methicillin-resistant S. aureus (MRSA) poses a serious threat to public health globally. Reuse of metal-based antimicrobials stands for one of the most promising strategies to resensitize drug resistant bacteria ...
ORGANISM(S): Staphylococcus aureus 
2021-09-10 | PXD025106 | Pride
Silver-binding protein S. aureus 
TranscriptomicsC1 evolved adaptive clones M1-M5
Chemostat evolution experiment C1 under glucose-limited condition at 30C. Gene Expression profiles of adaptive clones M1-M5 in evolved conditions compared with original parents. An all pairs experiment design type is where all labeled extracts are compared to every other labeled extract. Genotype: ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-08-20 | E-GEOD-11071 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization Streptomyces coelicolor A3(2) strains
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-21 | E-SMDB-2740 | biostudies-arrayexpress
UnknownHydroxyhydroquinone impairs fat utilization in mice by reducing nitric oxide availability.
Not available
S-EPMC6223984 | biostudies-literature
UnknownSkin-Protective Performance of Alternative Stratum Corneum Formed by a Pseudo-Ceramide-Containing Steroid Lamellar Cream.
Not available
S-EPMC11894917 | biostudies-literature
TranscriptomicsS. erythraea R5 Fall 2002 RNA Timecourse
Saccharopolyspora erythraea NRRL2338 (wildtype) and K41-135 (overproducer strain from Kosan Biosciences, KOVP) were grown in shake flask cultures in rich medium R5. RNA samples were harvested for each strain over 5 days. 12 h samples taken for each strain were used as their respective reference (&...
ORGANISM(S): Streptomyces coelicolor 
2005-07-26 | E-GEOD-2996 | biostudies-arrayexpress
UnknownA genome-wide analysis reveals no nuclear dobzhansky-muller pairs of determinants of speciation between S. cerevisiae and S. paradoxus, but suggests more complex incompatibilities.
Not available
S-EPMC2912382 | biostudies-literature
UnknownFunctional analysis of human olfactory receptors with a high basal activity using LNCaP cell line.
Not available
S-EPMC9022881 | biostudies-literature
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