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TranscriptomicsProneurogenic ligands defined by modeling developing cortex growth factor communication networks
The neural stem cell decision to self-renew or differentiate is tightly regulated by its microenvironment. Here, we have asked about this microenvironment, focusing on growth factors in the embryonic cortex at a time when it is largely comprised of neural precursor cells (NPCs) and newborn neurons. ...
ORGANISM(S): Mus musculus 
2016-08-23 | E-GEOD-84482 | biostudies-arrayexpress
TranscriptomicsHigh expression of BMP pathway genes distinguishes a subset of Atypical Teratoid/Rhabdoid Tumors associated with shorter survival
Molecular profiling of tumors has proven a valuable tool for identification of prognostic and diagnostic subgroups in medulloblastomas, glioblastomas and other cancers. However, the molecular landscape of atypical teratoid / rhabdoid tumors (AT/RTs) remains largely unexplored. To address this issue,...
ORGANISM(S): Homo sapiens 
2011-09-21 | E-GEOD-28026 | biostudies-arrayexpress
TranscriptomicsClinical and Molecular Characteristics of Congenital Glioblastoma Multiforme
Congenital glioblastoma multiforme (cGBM) historically has been considered an aggressive tumor of infancy requiring extensive chemotherapy to achieve cure. We report on 4 patients at our institution with cGBMs who were treated with surgery and chemotherapy (carboplatin and etoposide every 21 days fo...
ORGANISM(S): Homo sapiens 
2012-05-20 | E-GEOD-32374 | biostudies-arrayexpress
UnknownOccult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial.
Not available
S-EPMC3221530 | biostudies-literature
ProteomicsProteomic analysis of adipocyte insulin resistance
Insulin resistance is a major risk factor for human metabolic diseases including type 2 diabetes, cardiovascular diseases and some cancers. We analysed the proteome analyses across in vitro and in vivo models of insulin resistance to find common features of insulin resistance and identified lower e...
ORGANISM(S): Mus musculus (Mouse) 
2018-02-07 | PXD005128 | Pride
Insulin resistance Mouse Adipocyte Adipose tissue Orbitrap Lc-ms/ms 
UnknownSafety of Macitentan for the Treatment of Portopulmonary Hypertension: Real-World Evidence from the Combined OPUS/OrPHeUS Studies.
Not available
S-EPMC10881949 | biostudies-literature
TranscriptomicsTranscription profiling of human lung cancer patients with sqamous cell or adenocarcinoma at different stages of disease to identify gene signatures to predict prognosis
Gene signatures were derived to separate high risk patients from low risk ones. Experiment Overall Design: 130 samples from 129 patients
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-4573 | biostudies-arrayexpress
TranscriptomicsDevelopment and Independent Validation of a Molecular Subtype in High Grade Serous Ovarian Cancer using Formalin Fixed Paraffin Embedded Tissue, Training set
High Grade Serous Ovarian Cancer (HGSOC) is a histopathological diagnosis and may represent multiple diseases at a molecular level. We investigated whether distinct molecular subgroups may influence treatment choice. The accompanying validation set of data has also been deposited in ArrayExpress und...
ORGANISM(S): Homo sapiens 
2020-12-21 | E-MTAB-2562 | biostudies-arrayexpress
UnknownSildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial.
Not available
S-EPMC5905634 | biostudies-literature
UnknownClinically Significant Neuroimaging Findings Among Pediatric Patients Presenting to the Emergency Department With Symptoms of Psychosis: A Multicenter Retrospective Study.
Not available
S-EPMC12517762 | biostudies-literature
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