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TranscriptomicsMolecular defense mechanisms of Barrett's metaplasia estimated by an integrative genomics
Barrett's esophagus is characterized by the replacement of squamous epithelium with specialized intestinal metaplastic mucosa. The exact mechanisms of initiation and development of Barrett's metaplasia remain unknown, but a hypothesis of successful adaptation against noxious reflux components has be...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-36223 | biostudies-arrayexpress
ProteomicsHuman bladder cancer and colon cancer quatitative MS/MS
We analyzed a set of 40 independently collected tumor tissue/control samples using a label-free quantitation single pass LC-MS/MS approach. In this set, 10 samples originated from a colon tumor (i.e. AC) and 10 from control non-malignant tissue samples (NCA), as well as 10 from BC samples and 10 fro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082886 | MassIVE
TranscriptomicsHepatic molecular alterations more than muscle's differentiate obese hyperphagic mice from those prolonged fed with the high-fat diet
Although mitochondrial dysfunctions are implicated in the pathogenesis of obesity, the molecular mechanisms underlying obesity-related metabolic abnormalities are still not well established. To acquire a comprehensive picture of mitochondrial molecular changes within metabolically active tissues, we...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-43691 | biostudies-arrayexpress
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