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TranscriptomicsMolecular response of Escherichia coli O157:H7 Sakai during dynamic changes in growth kinetics induced by an abrupt downshift in temperature and water activity
This experiment contains the transcriptomic dataset that constitutes part of an integrated transcriptomic and proteomic study monitoring the response of exponential phase E. coli O157:H7 Sakai cultures upon an abrupt downshift in temperature and water activity (from 35°C aw 0.993 to 14°C aw 0.967)...
ORGANISM(S): Escherichia coli 
2016-09-16 | E-MTAB-3969 | biostudies-arrayexpress
UnknownThe crystal structure of a bacterial class II ketol-acid reductoisomerase: domain conservation and evolution.
Not available
S-EPMC2253233 | biostudies-literature
TranscriptomicsTranscription profiling of E. coli K-12 and O157:H7 during exposure to acetic, lactic, and hydrochloric acid at pH 5.5
The foodborne pathogen Escherichia coli O157:H7 is commonly exposed to organic acid in processed and preserved foods, allowing adaptation and the development of tolerance to pH levels otherwise lethal. Since little is known about the molecular basis of adaptation of E. coli to organic acids, we stud...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-TABM-912 | biostudies-arrayexpress
TranscriptomicsGlobal genome response of Escherichia coli to temperature downshift
In a previous study we adopted an integrated transcriptomic and proteomic approach to determine the physiological response of E. coli O157:H7 Sakai during exponential phase growth under steady-state conditions relevant to low temperature and water activity conditions experienced during meat carcass ...
ORGANISM(S): Escherichia coli 
2014-10-18 | E-MTAB-2010 | biostudies-arrayexpress
TranscriptomicsGlobal genome response of Escherichia coli to water activity downshift
In a previous study we adopted an integrated transcriptomic and proteomic approach to determine the physiological response of E. coli O157:H7 Sakai during exponential phase growth under steady-state conditions relevant to low temperature and water activity conditions experienced during meat carcass ...
ORGANISM(S): Escherichia coli 
2014-10-18 | E-MTAB-2011 | biostudies-arrayexpress
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
TranscriptomicsAn essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
Type I interferons were discovered as the primary antiviral cytokines and are now known to serve critical functions in host defense against bacterial pathogens. Accordingly, established mediators of interferon antiviral activity may mediate previously unrecognized antibacterial functions. RNase-L is...
ORGANISM(S): Mus musculus 
2008-12-19 | E-GEOD-13530 | biostudies-arrayexpress
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | GSE70279 | GEO
TranscriptomicsDeciphering myeloma risk loci by eQTL analysis
Recent genome-wide association studies have identified single nucleotide polymorphisms (SNPs) at 7 loci influencing multiple myeloma (MM) risk. We generated expression quantitative trait loci (eQTL) data on malignant plasma cells from two patient series (totaling 848) to fine map the risk loci assoc...
ORGANISM(S): Homo sapiens 
2014-12-09 | E-MTAB-2299 | biostudies-arrayexpress
UnknownGenetic species identification and population structure of grouper Epinephelus coioides (Hamilton, 1822) collected from fish markets along the Persian Gulf and the Oman Sea.
Not available
S-EPMC9575682 | biostudies-literature
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