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TranscriptomicsLandscape of somatic allelic imbalances and copy number alterations in human lung carcinoma
Lung cancer is the worldwide leading cause of death from cancer. This GEO series correspond to one of the BAC aCGH data sets used as validation cohort for the study: Landscape of somatic allelic imbalances and copy number alterations in human lung cancer, Int J Cancer 2012. Genomic profiling of 78 l...
ORGANISM(S): Homo sapiens 
2012-10-09 | E-GEOD-29065 | biostudies-arrayexpress
ProteomicsMSLibrarian: Optimized predicted spectral libraries for DIA proteomics
Data-independent mass spectrometry is the method of choice for deep, consistent and accurate single-shot profiling in bottom-up proteomics. While classic workflows required auxiliary DDA-MS analysis of subject samples to derive prior knowledge spectral libraries for targeted quantification from DIA-...
ORGANISM(S): Mus musculus (Mouse) Saccharomyces cerevisiae (Baker's yeast) 
2022-01-17 | PXD028901 | Pride
Q-exactive Predicted spectral library Dia Hf-x Lfq bench 
UnknownPhysical Activity at Growth Induces Bone Mass Benefits Into Adulthood - A Fifteen-Year Prospective Controlled Study.
Not available
S-EPMC8770997 | biostudies-literature
ProteomicsCOVID-19 proteome profiling reveals resolution of inflammatory pathways and respiratory distress after DNase treatment
Severe COVID-19 can result in pneumonia and acute respiratory failure. Accumulation of mucus in the airways is a hall mark of the disease and can result in hypoxemia. Here, we show that quantitative proteome analysis of the sputum from severe COVID-19 patients reveal high levels of neutrophil extrac...
ORGANISM(S): Homo sapiens (Human) 
2021-07-05 | PXD021197 | Pride
Human plasma dia swath-ms covid-19 hf-x 
ProteomicsA pharmacoproteomic landscape of organotypic intervention responses in gram-negative sepsis
Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events are unclear. This has resulted in ineffective development of sepsis-specific biomarkers and therapies, and suboptimal treatment regimens in preventing and reversing ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD036847 | Pride
Mouse Antibiotics Tissue Sepsis Plasma Corticosteroids Proteome 
ProteomicsA pharmacoproteomic landscape of organotypic intervention responses in gram-negative sepsis
Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events are unclear. This has resulted in ineffective development of sepsis-specific biomarkers and therapies, and suboptimal treatment regimens in preventing and reversing ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD036832 | Pride
Mouse Antibiotics Tissue Sepsis Plasma Corticosteroids Proteome 
ProteomicsNeutrophil extracellular traps in the central nervous system: a novel therapeutic target in pneumococcal meningitis.
Neutrophils are crucial mediators of host defense and are recruited to the central nervous system in large numbers during acute bacterial meningitis caused by S. pneumoniae. Neutrophils can release neutrophil extracellular traps (NETs) during infections to trap and kill bacteria. Intact NETs are fib...
ORGANISM(S): Homo sapiens (Human) Streptococcus pneumoniae TIGR4 
2019-11-12 | PXD011546 | Pride
Nets neutrophil pneumococci meningitis dda swath 
TranscriptomicsGenome-wide DNA methylation analysis of lung carcinoma
Lung cancer is the worldwide leading cause of death from cancer. DNA methylation in gene promoter regions is a major mechanism of gene expression regulation that may promote tumorigenesis. However, whether clinically relevant subgroups based on DNA methylation patterns exist in lung cancer is not we...
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-56044 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation analysis of lung carcinoma : Gene expression data
Lung cancer is the worldwide leading cause of death from cancer. DNA methylation in gene promoter regions is a major mechanism of gene expression regulation that may promote tumorigenesis. Experimental Design Whole-genome DNA methylation analysis using 450K Illumina BeadArrays was performed on ...
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-60644 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation and expression analysis of lung carcinoma
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-10-05 | E-GEOD-60645 | biostudies-arrayexpress
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