Sort   by:  
 Page size 
TranscriptomicsRNA-seq of human uveal melanoma cell lines 92-1, MP41 and UM22 treated with entinostat, JQ1 or DMSO
As part of the preclinical research for a recently published trial of combination therapy with the HDAC inhibitor entinostat and the PD1 inhibitor pembrolizumab, an experiment was performed to determined the influence of entinostat and the BET inhibitor JQ1 on the transcriptome of three uveal melano...
ORGANISM(S): Homo sapiens 
2021-09-09 | E-MTAB-11058 | biostudies-arrayexpress
UnknownEarly N-Terminal Pro B-Type Natriuretic Peptide (NTproBNP) Plasma Values and Associations with Patent Ductus Arteriosus Closure and Treatment-An Echocardiography Study of Extremely Preterm Infants.
Not available
S-EPMC8837127 | biostudies-literature
ProteomicsProtein paucimannosylation is a novel N-glycosylation signature of human cancers
While aberrant protein glycosylation is a recognised characteristic of human cancers, advances in glycoanalytics continue to discover new associations between glycoproteins and tumourigenesis. This glycomics-centric study investigates a possible link between protein paucimannosylation, an under-stud...
ORGANISM(S): Homo sapiens (Human) 
2021-03-07 | PXD014271 | Pride
Cancer / glycomics / glycan / protein paucimannosylation / paucimannosidic glycan 
UnknownComparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines : HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
Not available
S-EPMC4848167 | biostudies-literature
TranscriptomicsTranscriptomic characterization of the human cell cycle in individual unsynchronized cells
Here, we profiled transcription across the cell cycle in single human myxoid liposarcoma cells, without prior synchronization. Flourescence-activated cell sorting was used to infer G1, S or G2/M cell cycle stages after staining cells for DNA content. Single-cell RNA-sequencing was performed accordin...
ORGANISM(S): Homo sapiens 
2017-11-09 | E-MTAB-6142 | biostudies-arrayexpress
GenomicsA network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic stem/progenitor cells [ChIP-seq]
Transforming growth factor-β (TGFβ) is a potent inhibitor of hematopoietic stem cell (HSC) proliferation. However, the precise mechanism for this effect is unknown. Here, we have identified the transcription factor Gata2, previously described as an important regulator of HSC function, as an early ...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-73641 | biostudies-arrayexpress
TranscriptomicsStage-specific IFN-induced and IFN gene expression reveals convergence of type I and type II IFN and highlights their role in both acute and chronic phases of pathogenic SIV infection
Interferons (IFNs) play a major role in controlling viral infections including HIV/SIV infections. Persistent up-regulation of interferon stimulated genes (ISGs) is associated with chronic immune activation and progression in SIV/HIV infections, but the respective contribution of different IFNs is u...
ORGANISM(S): Macaca fascicularis 
2017-10-30 | E-MTAB-6068 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Drosophila melanogaster to count absolute number of molecules using unique molecular identifiers
Drosophila melanogaster mRNA sequencing using unique molecular identifiers (umis).
ORGANISM(S): Drosophila melanogaster 
2011-11-21 | E-MTAB-816 | biostudies-arrayexpress
UnknownAmplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia.
Not available
S-EPMC10191887 | biostudies-literature
ProteomicsGlycosylation of somatic extracts and secretome in the infective stage of the helminth Fasciola hepatica
Fasciola hepatica is a global helminth parasite of humans and their livestock. The invasive stage of the parasite, the newly excysted juvenile (NEJs), relies on glycosylated excretedsecreted (ES) products and surface/somatic molecules to interact with host cells and tissues and to evade the host's i...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2024-01-26 | PXD045488 | Pride
Glycoproteomics Orbitrap Parasites Glycosylation Lc-ms/ms 
Sort   by:  
 Page size