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TranscriptomicsIdentification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross
To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6J x A/J F2 (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the popu...
ORGANISM(S): Mus musculus 
2011-01-13 | E-GEOD-25506 | biostudies-arrayexpress
TranscriptomicsAgilent Mouse liver gene expression profiling of Cross B6/J x A/J
Mapping the genetic architecture of RNA transcript abundances has potential for revealing molecular mechanisms underlying complex traits like disease. Gene expression microarrays allow monitoring genetic control on a whole transcriptome level, but validity and reproducibility of microarray data is a...
ORGANISM(S): Mus musculus 
2011-02-02 | E-GEOD-20901 | biostudies-arrayexpress
TranscriptomicsAffymetrix Mouse liver gene expression profiling of Cross B6/J x A/J
Summary Mapping the genetic architecture of RNA transcript abundances has potential for revealing molecular mechanisms underlying complex traits like disease. Gene expression microarrays allow monitoring genetic control on a whole transcriptome level, but validity and reproducibility of microarray d...
ORGANISM(S): Mus musculus 
2011-02-02 | E-GEOD-20902 | biostudies-arrayexpress
TranscriptomicsGenomeTiling
Samples were purchased from Clontech as mRNA. Hybridization material was generated through a random-priming amplification procedure (RP-AMP) using primers with a random sequence at the 3' end and a fixed motif at the 5' end. shDNP256 (first strand synthesis): 5'- TAG ATG CTG TTG NNN NNN NNN -3' sh...
ORGANISM(S): Homo sapiens 
2004-03-03 | E-GEOD-1097 | biostudies-arrayexpress
TranscriptomicsRosetta (Merck) Expression Validated Gene Hybridizations
Rosetta (Merck) Expression Validated Gene Hybridizations
ORGANISM(S): Homo sapiens 
2003-12-17 | E-GEOD-918 | biostudies-arrayexpress
TranscriptomicsMapping the Genetic Architecture of Gene Expression in Human Liver
To uncover the genetic determinants affecting expression in a metabolically active tissue relevant to the study of obesity, diabetes, atherosclerosis, and other common human diseases, we profiled 427 human liver samples on a comprehensive gene expression microarray targeting greater than 40,000 tran...
ORGANISM(S): Homo sapiens 
2008-05-07 | E-GEOD-9588 | biostudies-arrayexpress
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