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TranscriptomicsTri-KIX +/- c-Myb MEFs
Transcription profiling by array of wild type and p300 KIX/KIX; CBP +/KIX primary mouse embryonic fibroblasts (MEFs) transduced with either MSCV-c-Myb_IRES-GFP or MSCV-IRES-GFP retrovirus to determine the effect of mutating the KIX domain of CBP and p300 on c-Myb regulated gene expression. CBP KIX ...
ORGANISM(S): Mus musculus 
2014-02-10 | E-MTAB-1973 | biostudies-arrayexpress
Unknown3-Deoxy-D-manno-octulosonic acid (Kdo) hydrolase identified in Francisella tularensis, Helicobacter pylori, and Legionella pneumophila.
Not available
S-EPMC2966046 | biostudies-literature
TranscriptomicsExpression data for Lck-Cre, Med23flox/flox and Med23flox/flox;Lck-Cre thymocytes +/- 3hr exposure to plate bound anti-CD3 antibody
MED23, a subunit of the Mediator coactivator complex, is important for the expression of a subset of MAPK/ERK pathway-dependent target genes; however, the genes in this subset varies between cell types. MAPK/ERK pathway-dependent processes are essential for T-cell development and function, but whet...
ORGANISM(S): Mus musculus 
2014-07-30 | E-GEOD-57061 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
RNA sequencing was performed on sorted populations of Lgr6-positive and Lgr6-negative keratinocytes from the interfollicular epidermis and the hair follicle/sebaceous gland, in order to determine the compartment-specific expression signatures of Lgr6+ progenitor cells.
ORGANISM(S): Mus musculus 
2015-10-22 | E-MTAB-3533 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic fibroblasts normoxia/hypoxia treatments with mutations in the CH1 domains of p300 and CBP
The CH1 (TAZ) domain of the transcriptional coactivators p300 and CBP has been reported to interact with the transcription factor HIF-1alpha and this interaction is thought to be critical for HIF-1alpha target gene expression in response to hypoxia. To determine the requirement for the CH1 domain i...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3195 | biostudies-arrayexpress
ProteomicsGeneration of aggregates of alpha-lactalbumin by UV-B light exposure
Whey proteins are widely used as ingredients in the form of aggregates to obtain certain functionalities in food applications. The aim of this study was to understand how UV illumination generates aggregates of alpha-lactalbumin (a-LA) as an alternative to heat treatments traditionally used for indu...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2019-12-16 | MSV000084695 | MassIVE
TranscriptomicsQuantitative single-cell RNA-seq
Purpose: We applied cDNA molecule counting using unique molecular identifiers combined with high-throughput sequencing to study the transcriptome of individual mouse embryonic stem cells, with spike-in controls to monitor technical performance. We further examined transcriptional noise in the embryo...
ORGANISM(S): Mus musculus 
2013-12-20 | E-GEOD-46980 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic fibroblasts C57Bl/6x129/Sv F2 e14.5 embryos vs controls grown in hypoxic or normoxic conditions
The CH1 protein interaction domain of the transcriptional coactivators p300 and CBP is thought to interact with HIF-1alpha and this interaction is thought to be critical to the expression of HIF-1alpha target genes in response to hypoxia. To test the requirement of the CH1 domain for gene expression...
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-3196 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and Clcn7-/- mouse hippocampus at p14
Comparison of expression levels between wild type and Clcn7-/- mouse hippocampus at p14. 3 wild type and 3 mutant mice were studied.
ORGANISM(S): Mus musculus 
2005-03-01 | E-MEXP-242 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 5 strains of Paxillus filamentosus and 1 strain of Paxillus involutus
Variations in gene content and sequence that could be associated with symbiotic adaptations of the ectomycorrhizal fungus Paxillus involutus were investigated by analyses of strains showing various abilities to form mycorrhiza. Five strains of Paxillus involutus (ATCC 200175, Maj; Nau, Pi01SE, and P...
ORGANISM(S): Paxillus filamentosus 
2006-01-01 | E-MEXP-437 | biostudies-arrayexpress
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