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TranscriptomicsTranscription profiling of human control (hMSC-TERT) vs Dlk overexpressing cells (hMSC-Dlk1) to analyse Dlk1-mediated signaling pathways during hMSC differentiation
We aimed in this study to identify the differentially regulated genes by Dlk1 in hMSC cells using microarray technology in order to gain a better understanding of Dlk1-mediated signaling pathways during hMSC differentiation. Both control (hMSC-TERT)(not expressing Dlk1) and Dlk1 overexpressing cells...
ORGANISM(S): Homo sapiens 
2006-02-10 | E-MEXP-560 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression profiling during Adipocytic differentiation of human MSCs (hMSC-TERT)
We have employed whole microRNA microarray to identify changes in microRNA expression in human bone marrow MSCs (hMSC-TERT) during adipocytic differentiation in culture on day 7 and day 13 Human MSC line (hMSC-TERT) were subjectd to adipocytic differentiation for 7 days or 13 days, subsequently, RNA...
ORGANISM(S): Homo sapiens 
2014-09-09 | E-GEOD-59684 | biostudies-arrayexpress
TranscriptomicsAssociation between in vivo bone formation and ex vivo migration capacity of human bone marrow stromal cells
Introduction: There is a clinical need for developing systemic transplantation protocols for use of human skeletal stem cells (also known bone marrow stromal stem cells) (hBMSC) in tissue regeneration. In systemic transplantation studies, only a limited number of hBMSC home to injured tissues sugges...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-69358 | biostudies-arrayexpress
TranscriptomicsThe Histone H2B Monoubiquitination Regulatory Pathway is Required for Differentiation of Multipotent Stem Cells
Extensive changes in post-translational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation. However, the mechanisms controlling the changes in specific chromatin modifications and their function during differentiation remain only poorly under...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-38173 | biostudies-arrayexpress
TranscriptomicsDLK1 Is a Novel Regulator of Bone Mass That Mediates Estrogen-Deficiency Induced Bone Loss in Mice
DLK1/FA-1 (delta-like 1/fetal antigen-1) is a transmembrane protein belonging to Notch/Delta family that acts as a membrane-associated or a soluble protein to regulate regeneration of a number of adult tissues. Here, we examined the role of DLK1/FA-1 in bone biology using osteoblast-specific-Dlk1 ov...
ORGANISM(S): Mus musculus 
2010-10-15 | E-GEOD-22113 | biostudies-arrayexpress
ProteomicsHs_HESC_Phospho_Silac_PMA_2r
hESCs cultured treated with PMA for 0min, 1hr or 24hr
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe005269 | PeptideAtlas
ProteomicsHs_HESC_Phospho_Silac_PMA_1
hESCs cultured treated with PMA for 0min, 30min or 6hr
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe005268 | PeptideAtlas
ProteomicsHs_HESC_Phospho_Silac_NCM_2
hESCs cultured treated with nonconditioned medium (NCM) for 0min, 1hr or 24hr.
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe005255 | PeptideAtlas
ProteomicsHs_HESC_Phospho_Silac_PMA_2
hESCs cultured treated with PMA for 0min, 1hr or 24hr
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe005235 | PeptideAtlas
ProteomicsHs_HESC_Phospho_Silac_NCM_2r
hESCs cultured treated with nonconditioned medium (NCM) for 0min, 1hr or 24hr.
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe005298 | PeptideAtlas
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