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UnknownAn Enhanced Retroviral Vector for Efficient Genetic Manipulation and Selection in Mammalian Cells.
Introducing genetic material into hard-to-transfect mammalian cell lines and primary cells is often best achieved through retroviral infection. An ideal retroviral vector should offer a compact, selectable, and screenable marker while maximizing transgene delivery capacity. However, a previously pub...
S-EPMC11430422 | biostudies-literature
UnknownIntegration of Inkjet Printed Graphene as a Hole Transport Layer in Organic Solar Cells
Not available
S-EPMC10608915 | biostudies-literature
UnknownRevealing the location and dynamics of a concealed binding site in the dopamine transporter.
The dopamine transporter (DAT) is linked to neuropsychiatric disorders including ADHD, Parkinson's disease, and substance use disorders. Accordingly, DAT is the target of illicit drugs and clinically important medicines. However, the number and function of ligand binding sites in DAT is enigmatic du...
S-EPMC12056086 | biostudies-literature
UnknownSingle HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1.

Background

H5N1 influenza vaccines, including live intranasal, appear to be relatively less immunogenic compared to seasonal analogs. The main influenza virus surface glycoprotein hemagglutinin (HA) of highly pathogenic avian influenza viruses (HPAIV) was shown to be more susceptible to acid...
S-EPMC3072404 | biostudies-literature
UnknownQuality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB™): 2-year results from the GABI-R-registry.

Background

Numerous studies have reported clinical endpoints following coronary revascularization using bioresorbable vascular scaffolds (BVS), while information about the impact on health-related quality of life is sparse. In this analysis of the German-Austrian ABSORB RegIstRy, the 2 year ...
S-EPMC9392935 | biostudies-literature
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