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UnknownRopivacaine represses the proliferation, invasion, and migration of glioblastoma via modulating the microRNA-21-5p/KAT8 regulatory NSL complex subunit 2 axis.
Not available
S-EPMC8973733 | biostudies-literature
GenomicsChiP-seq profiling of Drosophila melanogaster salivary glands to identify targets for NSL1 and MCRS2.
ChiP-seq profiling of Drosophila melanogaster salivary glands to identify targets for NSL1 and MCRS2.
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-MTAB-214 | biostudies-arrayexpress
ProteomicsKansl2 dependent acetylome study in primary Kansl2 (fl/fl) murine embryonic fibroblasts
As one of the most important post-translational protein modifications, lysine acetylation is catalyzed by lysine acetyltransferases (KATs), which catalyze the covalent attachment of an acetyl group to the N epsilon–residue of lysine. The histone acetyltransferase MOF, which represents the main histo...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-05 | PXD038521 | Pride
Kat8 regulatory nsl complex subunit 2  mef (murine embryonic fibroblast)  primary inducible kansl2 knock-out  cre-ert2  anti acetyl-lysine antibody  ptm enrichment 
TranscriptomicsRNAi profiling by array of Drosophila salivary glands upon NSL3, MCRS2 and MBDR2 RNAi mediated depletion
Expression profiling of NSL3, MCRS2 and MBDR2 RNAi-mediated depletion in Drosophila salivary glands. This experiment is related to experiment E-MTAB-214
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-MEXP-2652 | biostudies-arrayexpress
TranscriptomicsThe histone modifier KANSL2 is an actionable biomarker in multiple myeloma
Epigenetic aberrations are key drivers of multiple myeloma (MM), yet targeted therapies exploiting epigenetic alterations have not been established. By integrating clinical and molecular MM patient data sets with an unbiased genetic in vivo screen, we identified KAT8 regulatory NSL complex subunit 2...
ORGANISM(S): Homo sapiens 
2026-06-10 | GSE302047 | GEO
ProteomicsThe histone modifier KANSL2 is an actionable biomarker for response to epigenetic modifiers in multiple myeloma
Epigenetic aberrations are key drivers of multiple myeloma (MM), yet targeted therapies exploiting epigenetic alterations have not been established. By integrating clinical and molecular MM patient data sets with an unbiased genetic in vivoscreen, we identified KAT8 regulatory NSL complex subunit 2 ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-22 | PXD066205 | Pride
Histone acetylation Hdac inhibitors Kansl2 Bet inhibitors Biomarker Multiple myeloma 
UnknownEpigenetic regulation of autophagy-related genes: Implications for neurodevelopmental disorders.
Not available
S-EPMC10761153 | biostudies-literature
TranscriptomicsExpression data from mouse ES cells after control RNAi (scramble siRNAs) or specific RNAi (siRNAs for specific genes) treatment
To address the functional role of MOF in mammalian X upregulation, male and female mouse ES cells were transfected with a mixture of three small interfering RNA duplexes, each of which targets a different region of Mof mRNA. We found that MOF knockdown in mouse ES cells caused a greater drop in expr...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-44252 | biostudies-arrayexpress
GenomicsThe histone modifier KANSL2 is an actionable biomarker in multiple myeloma
The histone modifier KANSL2 is an actionable biomarker in multiple myeloma
PRJNA1288416 | ENA
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