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TranscriptomicsGene expression profiling of age-related EBV-positive B-cell lymphoproliferative disorders uncovers alterations in characteristic oncogenetic pathways: possible implications for pathogenesis
Comprehensive gene expression profiles of Epstein-Barr virus (EBV)-associated B cell neoplasm (clinical samples + cell lines)
ORGANISM(S): Homo sapiens 
2014-04-11 | E-MTAB-973 | biostudies-arrayexpress
TranscriptomicsSNP data from lymphoma samples
B cell non-Hodgkin's lymphoma (B-NHL) consists of different pathological entities that are frequently characterized by distinct genetic alterations. However, the knowledge on these genetic lesions in B-NHL is still limited. In order to obtain a more comprehensive view of genetic lesions in B-NHL, we...
ORGANISM(S): Homo sapiens 
2009-05-01 | E-GEOD-12906 | biostudies-arrayexpress
TranscriptomicsFracture healing in osteoporotic mice
Genome-wide comparative gene expression analysis of callus tissue of osteoporotic mice (Col1a1-Krm2 and Lrp5-/-) and wild-type were performed to identify candidate genes that might be responsible for the impaired fracture healing observed in Col1a1-Krm2 and Lrp5-/- mice. To investigate bone healing ...
ORGANISM(S): Mus musculus 
2013-10-25 | E-GEOD-51686 | biostudies-arrayexpress
TranscriptomicsCell cycle-regulated gene expression in tobacco cells
Tobacco BY-2 cells can be highly synchronized by treatment with an inhibitor of DNA synthesis, aphidicolin. For comprehensive understanding of cell cycle-regulated gene expression in tobacco, microarray analysis was conducted in synchronized cultures of BY-2 cells. Cells were treated with aphidicoli...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14250 | biostudies-arrayexpress
TranscriptomicsHistone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast.
In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its SRI domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser2 and Ser5 (CTD-S2,5-P). H3K36me2 recruits the Rpd3S histone deacetylase complex to repress crypt...
ORGANISM(S): Schizosaccharomyces pombe 
2016-02-04 | E-GEOD-66821 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of fission yeast silencing mutants
Array-based transcriptome analysis of spt6 deletant and spt6-K20.
ORGANISM(S): Schizosaccharomyces pombe 
2013-11-14 | E-MTAB-1373 | biostudies-arrayexpress
TranscriptomicsChanges in expression of small non-coding RNAs/microRNAs during aging in C. elegans
We report a significant number of miRNAs and other non-coding small RNAs show dramatic changes in expression during aging in C. elegans. RNAs were prepared from four diffrent timepoints during adulthood of C. elegans hermaphrodites, Day 0, 5, 8 and 12 post-L4 molt, and used for making cDNA libraries...
ORGANISM(S): Caenorhabditis elegans 
2009-12-31 | E-GEOD-18634 | biostudies-arrayexpress
TranscriptomicsHeme-Bound Iron Activates Placenta Growth Factor via Erythroid KrM-CM-
We have tested the effect of iron on the gene expression profile in human leukemia cells with properties of erythroid differentiation. 12 Total samples were analyzed. We compared the gene expression profiles of cells treated with iron mesoporphyrin to mesoporphyrin alone. DMSO vehicle was also teste...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-52087 | biostudies-arrayexpress
TranscriptomicsMethanosaeta thermophila ammonia stress
Effects of high concentration of ammonia were assessed by using mid-log phase cultures of Methanosaeta thermophila.
ORGANISM(S): Methanosaeta thermophila 
2013-04-01 | E-MEXP-3849 | biostudies-arrayexpress
TranscriptomicsDefinitive SNP/CNV haplotype map of Asians determined using a collection of complete hydatidiform moles (Illumina)
Copy number variations (CNVs) are abundant, possibly variable among populations, and can confer various phenotypic variations such as risk to complex disease. We determined a genome-wide high resolution SNP/CNV haplotype structure of Asians, by analyzing a collection of complete hydatidiform moles (...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-18663 | biostudies-arrayexpress
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