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no omics definedTranslation profiling of Arabidopsis cell cultures exposed to elevated temperature and high salinity
We investigated genome-wide changes in mRNA translation in Arabidopsis thaliana suspension cell cultures exposed to brief perids of two types of stress: elevated temperature (37 degree_C) and high salinity (200 mM NaCl). To this end, we subjected polysomal RNA and non-polysomal RNA from sucrose grad...
ORGANISM(S): Arabidopsis thaliana 
2010-07-07 | E-DORD-69 | biostudies-arrayexpress
TranscriptomicsOverexpression of NtmybA2 in tobacco BY-2 cells
Promoters of many G2/M phase-specific genes in plants contain mitosis-specific activator (MSA) elements, which act as G2/M phase-specific enhancers and bind with R1R2R3-Myb transcription factors. A least three R1R2R3-Myb proteins are expressed in tobacco (Nicotiana tabacum). To examine the genome-wi...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14251 | biostudies-arrayexpress
TranscriptomicsCell cycle-regulated gene expression in tobacco cells
Tobacco BY-2 cells can be highly synchronized by treatment with an inhibitor of DNA synthesis, aphidicolin. For comprehensive understanding of cell cycle-regulated gene expression in tobacco, microarray analysis was conducted in synchronized cultures of BY-2 cells. Cells were treated with aphidicoli...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14250 | biostudies-arrayexpress
TranscriptomicsContribution of NAC transcription factors to plant adaptation to land
The development of cells specialized for water conduction or support is a striking innovation of plants that has enabled them to colonize land. The NAC transcription factors regulate differentiation of these cells in vascular plants. However, the path by which plants with these cells have evolved fr...
ORGANISM(S): Physcomitrella patens 
2014-05-23 | E-MTAB-4115 | biostudies-arrayexpress
TranscriptomicsFinding direct target genes of VND7
Direct target genes of VND7 were explored with inducible expression system using glucocorticoid receptor (GR). Transgenic plants expressing 35S:VND7-VP16-GR were treated with dexamethazone (DEX) and/or protein synthesis inhibitor cycloheximide (CHX). A number of genes related to the formation of vas...
ORGANISM(S): Arabidopsis thaliana 
2011-03-31 | E-GEOD-24169 | biostudies-arrayexpress
TranscriptomicsmiR-130a activates apoptotic signaling through activation of caspase-8 in taxane-resistant prostate cancer cells [total RNA]
Background: The acquisition of drug resistance is one of the most malignant phenotypes of cancer. MicroRNAs (miRNAs) have been implicated in various types of cancers, but its role in taxane-resistance of prostate cancer remains poorly understood. Methods: In order to identify miRNAs related to taxan...
ORGANISM(S): Homo sapiens 
2015-07-31 | E-GEOD-64012 | biostudies-arrayexpress
TranscriptomicsmiR-130a activates apoptotic signaling through activation of caspase-8 in taxane-resistant prostate cancer cells [miRNA]
Background: The acquisition of drug resistance is one of the most malignant phenotypes of cancer. MicroRNAs (miRNAs) have been implicated in various types of cancers, but its role in taxane-resistance of prostate cancer remains poorly understood. Methods: In order to identify miRNAs related to taxan...
ORGANISM(S): Homo sapiens 
2015-07-31 | E-GEOD-64013 | biostudies-arrayexpress
UnknownA subanalysis of Japanese patients in a randomized, double-blind, placebo-controlled, phase 3 trial of nivolumab for patients with advanced gastric or gastro-esophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2).
Not available
S-EPMC6394726 | biostudies-literature
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