Sort   by:  
 Page size 
UnknownExpression of Interleukin-26 is upregulated in inflammatory bowel disease.
Not available
S-EPMC5558115 | biostudies-literature
TranscriptomicsDifferential gene expression profiling by LSD1 inhibition using novel LSD1 inhibitors (NCD25 and NCD38)
LSD1 is a demethylase of histone modification H3k4me1 and H3K4me2. We have developed novel LSD1 inhibitors (NCD25 and NCD38) and found that they are effective to myelodysplastic syndromes and leukemia cells. To understand what mechanisms are affected by these compounds, we employed gene expression p...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-68348 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially regulated genes upon overexpression of HLX in wild-type hematopoietic stem cells
The goal was to study the role of Hlx in hematopoiesis. Sorted Lin-Kit+Sca-1+ cells from wild-type FVB/nJ bone marrow were infected with control (pCAD-IRES-GFP) or Hlx lentivirus (pCAD-IRES-GFP-Hlx) and cultured for 2 days in Iscove’s modified Dulbecco’s medium (IMDM) containing FBS, mIL-3, mIL-6 an...
ORGANISM(S): Mus musculus 
2012-09-14 | E-GEOD-27938 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially regulated genes upon shRNA-mediated knock-down of HLX in the URE leukemia cell line
To study the role of Hlx in hematopoietic differentiation and tumorigenesis, URE cells were infected with short-hairpin-containing pSIH1-H1-copGFP lentiviral vector (System Biosciences, Mountain View, CA) containing either nucleotide sequences targeting luciferase (shControl) or HLX (shHLX). After 2...
ORGANISM(S): Mus musculus 
2012-09-14 | E-GEOD-27939 | biostudies-arrayexpress
Sort   by:  
 Page size