Sort   by:  
 Page size 
TranscriptomicsWhole-genome microarray analysis of primary, secondary, tertiary and quaternary memory CD8 T cells
The transcriptome of naive OT-I T cells was compared to memory CD8 T cells after 1, 2, 3, or 4 infection with ovalbumin expressing Listeria monocytogenes (LM-OVA). Naive Thy1.1 OT-I T cells were adoptively transferred into Thy1.2 naive hosts prior to infection with LM-OVA. The resulting memory CD8 T...
ORGANISM(S): Mus musculus 
2010-07-09 | E-GEOD-21360 | biostudies-arrayexpress
TranscriptomicsExpression data from WT and IL-2 secondary CD4 T cell effectors responding towards infuenza A virus infection
How IL-2 produced by secondary CD4 T cell effectors, derived from resting memory cells, impacts memory CD4 T cell function and survival to memory following antigen re-encounter is unknown. We used microarrays to detail the global programme of gene expression underlying differences between WT and IL-...
ORGANISM(S): Mus musculus 
2015-05-14 | E-GEOD-60186 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse naive CD4+CD25-CD62Lhi T cells and nTreg cells with Eos knock-down
Eos expression in Treg cells have been documented by several microarrays including ours. We hypothesized that Eos facilitates Foxp3- dependent gene repression in Regulatory T cells. In order to investigate the role of Eos in mediating the Foxp3-dependent gene silencing program, we utilized lentivir...
ORGANISM(S): Mus musculus 
2009-10-16 | E-GEOD-17166 | biostudies-arrayexpress
TranscriptomicsCMV-Specific CD8+ Memory T Cells Re-Emerge After Viral Challenge And Recapitulate CMV Immunity Under Various Adoptive Transfer Conditions
Reconstitution of cytomegalovirus (CMV)-specific immunity following transplant remains a primary clinical objective to prevent CMV disease, and adoptive immunotherapy of CMV-specific T cells can be an effective therapeutic approach. Due to the persistence of CMV, most CMV-specific CD8+ T cells becom...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-61927 | biostudies-arrayexpress
TranscriptomicsExpression data from DC-induced Hopx-deficient and sufficient regulatory T cells after immunization
We found that Hopx is required for the function of DC-induced regulatory T cells in vivo. We used microarrays to identify relevant Hopx-targets in such cells after antigenic re-challenge in vivo. CD25/Foxp3 double positive DC-induced Hopx-deficient and sufficient regulatory T cells were FACS sorted ...
ORGANISM(S): Mus musculus 
2010-08-29 | E-GEOD-23167 | biostudies-arrayexpress
TranscriptomicsExpression data from primary and secondary CD4 T cell effectors responding towards influenza A virus infection
How secondary CD4 T cell effectors, derived from resting memory cells, differ from primary cells, derived from naïve precursors, and how such differences impact recall responses to pathogens is unknown. We used microarrays to detail the global programme of gene expression underlying differences betw...
ORGANISM(S): Mus musculus 
2012-08-27 | E-GEOD-40230 | biostudies-arrayexpress
TranscriptomicsExpression data from stimulated or unstimulated human CD4+ T cells incubated with edelfosine
The cytotoxic drug edelfosine is a synthetic analog of 2-lysophosphatidylcholine. Edelfosine is incorporated by highly proliferating cells, e.g. activated immune cells. It is unknown if the described mechanisms for edelfosine action attained by in vitro approaches exclusively contribute to the obser...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44392 | biostudies-arrayexpress
UnknownIdentification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides.
Not available
S-EPMC8807680 | biostudies-literature
UnknownITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
Not available
S-EPMC2876982 | biostudies-literature
UnknownActivin a suppresses peripheral CD8+ T lymphocyte activity in acute-phase Kawasaki disease.
Not available
S-EPMC7903692 | biostudies-literature
Sort   by:  
 Page size