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TranscriptomicsExpression profiling in the heart of wild-type and kctd10 mutant zebrafish larvae
We sequenced mRNA of hearts from 50 wild-type and 50 kctd10 mutant embryos at 48 hpf. Examination of mRNA levels in the larvae hearts between the the wt and the kctd10 mutant.
ORGANISM(S): Danio rerio 
2013-12-06 | E-GEOD-53022 | biostudies-arrayexpress
ProteomicsMouse cortex immunoprecipitation-mass spectrometry
To determine the mechanism for how Kctd10 deficiency impacts brain development, co-immunoprecipitation (co-IP) was performed to identify KCTD10-interacting proteins from the E14.5 cerebral cortex using a KCTD10 antibody, followed by mass spectrometric analysis. In total, 143 proteins uniquely precip...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD050135 | Pride
E14.5 Mouse Kctd10 Crebral cortex 
ProteomicsMouse cortex quantitative LC-MS/MS analysis
Quantitative mass spectrometry (MS) comparing E14.5 WT and Kctd10-cKO cortical samples was performed to identify the functional consequence of KCTD10 loss on protein abundance. A total of 3,442 differentially expressed proteins (DEPs) were identified using three or more biological replicates.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-23 | PXD050077 | Pride
E14.5 Mouse Kctd10 Cerebral cortex 
GenomicsKCTD10 is a sensor for co-directional transcription-replication conflicts
KCTD10 is a sensor for co-directional transcription-replication conflicts
PRJNA1253961 | ENA
GenomicsKCTD10 is a sensor for co-directional transcription-replication conflicts
During DNA replication, the replisome must remove barriers and roadblocks including the transcription machinery. Transcription-replication conflicts (TRCs) occur when there are collisions between the replisome and transcription machinery, and are increasingly recognized as an important source of mam...
ORGANISM(S): Homo sapiens 
2025-07-31 | GSE295262 | GEO
UnknownKCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13.
Not available
S-EPMC10963008 | biostudies-literature
UnknownKCTD10 is a sensor for co-directional transcription-replication conflicts.
Not available
S-EPMC12675284 | biostudies-literature
UnknownInhibition of KCTD10 Affects Diabetic Retinopathy Progression by Reducing VEGF and Affecting Angiogenesis.
Not available
S-EPMC9629933 | biostudies-literature
TranscriptomicsExpression profiling in the heart of wild-type and kctd10 mutant zebrafish larvae
We sequenced mRNA of hearts from 50 wild-type and 50 kctd10 mutant embryos at 48 hpf.
ORGANISM(S): Danio rerio 
2013-12-06 | GSE53022 | GEO
UnknownGene expression network analysis of ETV1 reveals KCTD10 as a novel prognostic biomarker in gastrointestinal stromal tumor.
Not available
S-EPMC3747077 | biostudies-literature
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