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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
ProteomicsCircadian Mouse Articular Cartilage Proteomics
Mouse hip articular cartilage was collected every 4 hour for 48 hours and analysed by mass spec
ORGANISM(S): Mus musculus (Mouse) 
2021-03-01 | PXD019431 | Pride
Mouse Cartilage Circadian clock Oseoarthritis 
TranscriptomicsComparison of MicroRNA deep sequencing of matched formalin-fixed paraffin-embedded and fresh frozen cancer tissues
MicroRNAs regulate several aspects of tumorigenesis and cancer progression. Most cancer tissues are archived formalin-fixed and paraffin-embedded (FFPE). While microRNAs are a more stable form of RNA thought to withstand FFPE-processing and degradation there is only limited evidence for the latter a...
ORGANISM(S): Homo sapiens 
2013-04-15 | E-GEOD-45740 | biostudies-arrayexpress
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownLandscape and m<sup>6</sup>A post-transcriptional regulation of soybean proteome.
Not available
S-EPMC12534700 | biostudies-literature
UnknownThe inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication.
Not available
S-EPMC12036488 | biostudies-literature
UnknownAssociation between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety.
Not available
S-EPMC12487446 | biostudies-literature
UnknownSIRT1-based therapy targets a gene program involved in mitochondrial turnover in a model of retinal neurodegeneration.
Not available
S-EPMC12009334 | biostudies-literature
UnknownVersatile polymer-coated Ag<sub>2</sub>Se thermoelectric materials and devices for multi-scenario applications developed by direct-ink printing.
Not available
S-EPMC12475023 | biostudies-literature
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