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ProteomicsBone Morphogenetic Protein 9 Protects against Myocardial Infarction by Improving Lymphatic Drainage Function and Triggering DECR1-Mediated Mitochondrial Bioenergetics
We investigated the impact of both BMP9 deficiency and replenishment on the pathogenesis of MI in mice. Our results showed an aggravated pathological phenotype of MI in BMP9 knockout (KO) mice, which can be alleviated by replenishment of BMP9. Therefore, we further investigated the mechanism whereby...
ORGANISM(S): Mus Musculus 
PXD051517 |
MetabolomicsEssential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain

Omega-3 fatty acids (n-3 polyunsaturated fatty acids; n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low maternal intake of n...

2020-11-03 | MTBLS1952 | MetaboLights
UnknownLeft ventricular thrombus formation in myocardial infarction is associated with altered left ventricular blood flow energetics.
Not available
S-EPMC6302263 | biostudies-literature
UnknownAcrylamide disrupts meiotic G2/M transition and SAC activity during oocyte maturation.
Not available
S-EPMC12933907 | biostudies-literature
UnknownGenome-Wide Characterization of PIN Auxin Efflux Carrier Gene Family in Mikania micrantha.
Not available
S-EPMC9456128 | biostudies-literature
MetabolomicsMolecular networking coupled to high-resolution mass spectrometry fragmentation reveals a multitude of urinary antihypertensive drug metabolites
Mass spectrometry is the current technique of choice in studying drug metabolism. High-resolution mass spectrometry (HR-MS) in combination with fragment analysis (MS/MS) has the potential to contribute to rapid advances in this field. However, the data emerging from such fragmentation spectra pose c...
2016-05-23 | MTBLS307 | MetaboLights
MetabolomicsVegetable Signatures Derived from Human Urinary Metabolomic Data in Controlled Feeding Studies
Examination of changes in urinary metabolomic profiles after vegetable ingestion may lead to new methods of assessing plant food intake. To this regard, we developed a proof-of-principle methodology to identify urinary metabolomic signatures for spinach, celery, and onion. Three feeding studies were...
2019-05-30 | MTBLS683 | MetaboLights
UnknownAssociations Between Perceived Parental and Michigan Middle-School Students' Lifestyle Characteristics.
Not available
S-EPMC11562258 | biostudies-literature
UnknownPopulation allocation at the housing unit level: estimates around underground natural gas storage wells in PA, OH, NY, WV, MI, and CA.
Not available
S-EPMC6613251 | biostudies-literature
ProteomicsPreclinical Evaluation of seco-Duocarmycin SA in Aggressive Glioblastoma Cell Lines
Glioblastoma multiforme (GBM) is among the most lethal primary brain tumors and is characterized by significant cellular heterogeneity and resistance to conventional therapies. This study investigates the efficacy of seco-duocarmycin SA (seco-DSA), a novel DNA alkylating agent. Initial investiga-tio...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD061023 | Pride
Proof of concept Glioblastoma multiforme Resistance Cellular mechanisms Seco-dsa Duocarmycin Potency 
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