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ProteomicsPreclinical Evaluation of seco-Duocarmycin SA in Aggressive Glioblastoma Cell Lines
Glioblastoma multiforme (GBM) is among the most lethal primary brain tumors and is characterized by significant cellular heterogeneity and resistance to conventional therapies. This study investigates the efficacy of seco-duocarmycin SA (seco-DSA), a novel DNA alkylating agent. Initial investiga-tio...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD061023 | Pride
Proof of concept Glioblastoma multiforme Resistance Cellular mechanisms Seco-dsa Duocarmycin Potency 
UnknownBorylation via iridium catalysed C-H activation: a new concise route to duocarmycin derivatives.
Not available
S-EPMC11234497 | biostudies-literature
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