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GenomicsHomo sapiens KEL gene for Kell blood group system, KEL(R192Q) allele, exons 1-19.
First observation of a mutation (R192Q) in a weak KEL2 phenotype encoded by 575 G>A, ethnic origin: Austria.
PRJEB46130 | ENA
UnknownFunctional Evaluation of KEL as an Oncogenic Gene in the Progression of Acute Erythroleukemia.
Not available
S-EPMC8819426 | biostudies-literature
UnknownCDDO-Imidazole regulates RBC alloimmunization to the KEL antigen by activating Nrf2.
Not available
S-EPMC11996576 | biostudies-literature
GenomicsKo_null phenotype c.1414-1G>T
A novel KEL*02.03 with c.1414-1G>T SNV found in the Polish family leading to Ko_null phenotype
PRJEB40420 | ENA
UnknownPoly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice.
Not available
S-EPMC7256361 | biostudies-literature
UnknownB cells require Type 1 interferon to produce alloantibodies to transfused KEL-expressing red blood cells in mice.
Not available
S-EPMC5745367 | biostudies-literature
UnknownType 1 IFN signaling critically regulates influenza-induced alloimmunization to transfused KEL RBCs in a murine model.
Not available
S-EPMC6785373 | biostudies-literature
UnknownData on master regulators and transcription factor binding sites found by upstream analysis of multi-omics data on methotrexate resistance of colon cancer.
Not available
S-EPMC5196090 | biostudies-literature
ProteomicsUbiquitin Proteomics Analysis of Systemic Sclerosis Lung Fibroblasts with or without KLHL42 knockdown
Systemic scleroderma (SSc) is an autoimmune disease which results in fibrotic production in the lung. Resultant SSC-pulmonary fibrosis is the main cause of mortality among SSc patients. From high throughput RNAi screening, we uncovered the ubiquitin E3 ligase KLHL42 as a potential pro-fibrotic media...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-14 | MSV000084800 | MassIVE
UnknownComplement serves as a switch between CD4+ T cell-independent and -dependent RBC antibody responses.
Not available
S-EPMC6302935 | biostudies-literature
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