Sort   by:  
 Page size 
ProteomicsThe bovine cumulus proteome of cumulus oocyte complexes that successfully matured or failed to mature after maturation in-vitro and in-vivo
The oocyte forms a complex with their somatic cumulus cells within the follicle throughout the preovulatory maturation steps. Cumulus cells support their oocyte not only through mechanical protection but also with a close bidirectional exchange of metabolites. Analysis of the oocytes cumulus gives t...
ORGANISM(S): Bos taurus (Bovine) 
2020-06-30 | PXD016679 | Pride
Cumulus Proteomics Oocyte 
ProteomicsRelating the equine « cumulome » to the developmental competence of the corresponding oocyte
In vitro maturation (IVM) of equine oocytes results in a reduced developmental capacity compared to in vivo matured oocytes. Cumulus cells mirror oocytal well-being through close bidirectional communication. After maturation, the cumulus complex is not required anymore. Therefore, these cells are a ...
ORGANISM(S): Equus caballus (Horse) 
2024-09-18 | PXD033551 | Pride
Cumulus Oocyte Ivf Equine Biomarker Proteomics Ivm 
UnknownINS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.
Not available
S-EPMC3268987 | biostudies-literature
TranscriptomicsThe systematic shortening of 3’ UTRs has limited influence on the relative change in protein abundance in proliferating cells
Alternative polyadenylation is an important cellular mechanism that enables generation of mRNA isoforms that differ in their 3' untranslated regions (3' UTRs) and consequently in their susceptibility to miRNA and RNA binding protein mediated regulation. A dramatic change in polyadenylation site usa...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-54950 | biostudies-arrayexpress
TranscriptomicsGenome?wide analysis of pre?mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length: A-seq
Through alternative polyadenylation, human mRNAs acquire longer or shorter 3' untranslated regions, the latter typically associated with higher transcript stability and increased protein production. To understand the dynamics of polyadenylation site usage, we mapped transcriptome?wide both binding s...
ORGANISM(S): Homo sapiens 
2012-05-15 | E-GEOD-37037 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length: CLIP
Through alternative polyadenylation, human mRNAs acquire longer or shorter 3' untranslated regions, the latter typically associated with higher transcript stability and increased protein production. To understand the dynamics of polyadenylation site usage, we mapped transcriptome‐wide both binding s...
ORGANISM(S): Homo sapiens 
2012-05-15 | E-GEOD-37398 | biostudies-arrayexpress
GenomicsPAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif [PAR-CLIP]
PAPD5 is one of the seven members of non-canonical poly(A) polymerases in human cells. There are previous reports about polyadenylation dependent degradation of pre-ribosomal RNAs and uridylation dependent degradation of histone mRNAs in vivo. In this study, we observed polyadenylation but not polyu...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-36987 | biostudies-arrayexpress
TranscriptomicsCleavage Factor Im as a key regulator of 3’ UTR length
In eukaryotes, the 3' ends of RNA polymerase II-generated transcripts are made in the majority of cases by site-specific endonucleolytic cleavage, followed by the addition of a poly(A) tail. By alternative polyadenylation, a gene can give rise to multiple mRNA isoforms that differ in the length of t...
ORGANISM(S): Homo sapiens 
2012-10-30 | E-GEOD-40137 | biostudies-arrayexpress
UnknownThe Enzymatic Core of the Parkinson's Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast.
Not available
S-EPMC6021522 | biostudies-literature
UnknownGene Expression Alterations in Peripheral Blood Following Sport-Related Concussion in a Prospective Cohort of Collegiate Athletes: A Concussion Assessment, Research and Education (CARE) Consortium Study.
Not available
S-EPMC11632067 | biostudies-literature
Sort   by:  
 Page size