Cumulus - OmicsDI

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Unknown (869)
Transcriptomics (281)
Genomics (266)
Proteomics (27)
Methylation profiling (5)
Other (2)
Metabolomics (2)
Genomic (1)

Organisms

Mus musculus (103)
Bos taurus (91)
Homo sapiens (88)
Bombyx mori (22)
Onchocerca volvulus (22)
Klebsiella pneumoniae (22)
Musca domestica (22)
Brugia malayi (22)
Schizosaccharomyces pombe (22)
Cnidaria (22)
Streptomyces coelicolor A3(2) (22)
Sus scrofa (22)
Human immunodeficiency virus 1 (22)
Oryza sativa Indica Group (22)
Sinorhizobium meliloti BL225C (22)
Vitis (22)
Sus scrofa domesticus (22)
Ostreococcus tauri (22)
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Oryctolagus cuniculus (1)
synthetic construct (1)
cellular organisms (1)

Organisms

Mus musculus (82)
Homo sapiens (55)
Bos taurus (50)
Sus scrofa (14)
Macaca mulatta (4)
Bos indicus (2)
unidentified (2)
Rattus norvegicus (2)
Ovis aries (2)
Bubalus bubalis (1)
Oryctolagus cuniculus (1)
Equus caballus (1)

Repository

ENA (244)
geo (161)
biostudies-arrayexpress (145)
pride (22)
ExpressionAtlas (3)
iProX (3)
jPOST (2)
MetaboLights (2)
dbGaP (1)
EGA (1)

Tissue

Oocyte (13)
Cumulus cell (8)
Ovarian cumulus cell (3)
Ovarian follicle (2)
Follicular cell of ovary (1)
Granulosa cell (1)
Follicular fluid (1)
Testis (1)
Cell culture (1)

Disease

Disease free (1)

Technology Type

Mass Spectrometry (22)
Shotgun proteomics (11)
Bottom-up proteomics (4)
Gel-based experiment (3)
Data-independent acquisition (2)
Data-dependent acquisition (2)
Top-down proteomics (2)
Mass spectrometry (1)
Mass spectrometry assay (1)
DiaPASEF (1)

Instrument Platform

NextSeq 2000 (4)
Illumina HiSeq 2000 (2)
VersArray ChipReader [Bio-Rad Laboratories] (1)
G2500A GeneArray scanner [Agilent Technologies] (1)
418 [Affymetrix] (1)
NextSeq 550 (1)
NextSeq 500 (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2013 (33)
2015 (32)
2024 (30)
2016 (28)
2012 (28)
2014 (21)
2011 (21)
2025 (19)
2008 (14)
2021 (14)
2020 (14)
2023 (13)
2010 (10)
2022 (10)
2018 (9)
2026 (8)
2017 (8)
2007 (7)
2009 (6)
2019 (5)
2006 (4)
2004 (2)
2005 (1)

CHEBI ID

CHEBI:138640 (1)
CHEBI:133396 (1)
CHEBI:81565 (1)
CHEBI:140933 (1)
CHEBI:140930 (1)
CHEBI:131888 (1)
CHEBI:34505 (1)
CHEBI:27696 (1)
CHEBI:63974 (1)
CHEBI:34130 (1)
CHEBI:34490 (1)
CHEBI:34157 (1)
CHEBI:34450 (1)
CHEBI:19138 (1)
CHEBI:60943 (1)
CHEBI:15544 (1)
CHEBI:15555 (1)
CHEBI:15553 (1)
CHEBI:28728 (1)
CHEBI:15551 (1)
CHEBI:16978 (1)
CHEBI:15647 (1)
CHEBI:15552 (1)
CHEBI:72651 (1)
CHEBI:72639 (1)
CHEBI:34306 (1)

Metabolite Name

Thr-Pro-Arg (1)
Thr-Gly-Arg (1)
Ser-Asp-Arg (1)
Pyroglu-Asn-Arg (1)
L-valine, n-[[1-(5-fluoropentyl)-1h-indol-3-yl]carbonyl]-, methyl ester (1)
Cys-His-Arg (1)
5-methoxy-4-methyl-3-phenylcoumarin (1)
4-phenylbutan-2-ol (1)
3-quinolinecarboxamide, 1,4-dihydro-8-methoxy-4-oxo-1-pentyl-n-tricyclo[3.3.1.13,7]dec-1-yl- (1)
2-methyl-6(s)-(3-pyridyl)tetrahydro-1,2-oxazine (1)
2-furancarboxylic acid, 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]- (1)
1h-indole-3-carboxylic acid, 1-(5-fluoropentyl)-, 8-quinolinyl ester (1)
[1,1':4',1''-terphenyl]-3,4'',5-triol (1)
[[4-[5r-chloro-2z-[3r-cyclohexyl-3s-hydroxy-1r-propenyl]-3s-hydroxycyclopentyl]-2r-butenyl]oxy]-acetic acid, isopropyl ester (1)
(s)-n-(1-amino-1-oxo-3-phenylpropan-2-yl)-1-pentyl-1h-indole-3-carboxamide (1)
(3as,5r,5as,8as,9ar)-5,8a-dimethyl-1-methylidene-3a,4,5,5a,6,7,9,9a-octahydroazuleno[6,7-b]furan-2,8-dione (1)
L-myo-inositol-1,4,5-triphosphate (1)
Arg-asp (1)
2-hdeahpda [dmed-fahfa] (1)
Mepirapim (1)
Glycerol trioleate (1)
Tyr-His-Arg (1)
Solasodine base + 2h, 1o, o-hex-hex-hex (1)
Cyanidin 3-o-[2''-o-(xylosyl)-6''-o-(p-o-(glucosyl)-p-coumaroyl) glucoside] 5-o-glucoside (1)
Combrestatin a4 (1)
6-oxomometasone furoate (1)
(z)-2-octylpent-2-enedioic acid (1)
Cocamidoprpylbetaine (1)
.alpha.-galactosyl-n-stearoylsphingosine (1)
Ser-Ser-Arg (1)

First Public Date

2014 (55)
2024 (36)
2025 (27)
2026 (18)
2021 (18)
2023 (16)
2020 (15)
2015 (15)
2022 (10)
2016 (10)
2018 (8)
2019 (6)
2017 (5)
2013 (5)

Study type

Transcription profiling by array (116)
RNA-seq of coding RNA (13)
RNA-seq of non coding RNA (7)
Methylation profiling by array (3)
RNA-seq of coding RNA from single cells (2)
Transcription profiling by SAGE (1)
ChIP-chip by tiling array (1)
Other (1)
ChIP-seq (1)

Release Date

2021 (100)
2022 (94)
2023 (92)
2020 (83)
2024 (65)
2015 (63)
2025 (62)
2018 (58)
2016 (50)
2019 (49)
2017 (48)
2014 (47)
2013 (44)
2012 (37)
2011 (36)
2010 (23)
2009 (18)
2008 (17)
2026 (8)
2007 (8)
2006 (4)
2005 (4)
2004 (3)
2002 (1)

Lab affiliation

Gamete Research Centre, Department of Veterinary Sciences, University of Antwerp, 2610 Wilrijk, Belgium. (1)
Department of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, the Hebrew University, Rehovot 76100, Israel Center of Excellence in Agriculture and Environmental Health, the Hebrew University, Rehovot 76100, Israel (1)
Fertility & Research Centre, School of Clinical Medicine, Faculty of Medicine & Health, University of New South Wales, Australia (1)
College of Animal Science and Technology, China Agricultural University.College of Animal Science and Technology, China Agricultural University. (1)
College of Animal Science, Shanxi Agricultural University (1)
INRAE Val de Loire UMR Physiologie de la reproduction et des comportements (1)
INRAE Val de Loire UMR Physiologie de la Reproduction et des Comportements (1)
Chongqing Key Laboratory of Human Embryo Engineering (1)
Chongqing Key Laboratory of Human Embryo Engineering, Center for Reproductive Medicine, Women and Children’s Hospital of Chongqing Medical University, Chongqing, China (1)
Clinic of Reproductive Medicine; Vetsuisse Faculty; University of Zurich (1)
University of Tennessee Institute of Agriculture, Animal Science (1)
University of Antwerp, Department of Veterinary Sciences, Laboratory of Veterinary Physiology and Biochemistry, Gamete Research Centre, Wilrijk, Belgium. (1)
Basic Sciences, College of Veterinary Medicine (1)
Friedrich-Loeffler-Institute (1)
Center of Reproductive Medicine, Huai’an Maternity and Child Health Care Hospital, Huai’an, 223002, P.R. China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, 210029, P.R. China (1)
State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 211166, China (1)
Department of Biomolecular Medicine, Ghent University, Ghent, Belgium VIB Center for Medical Biotechnology, VIB, Ghent, Belgium (1)
Nanjing Med Univ, State Key Lab Reprod Med, Dept Histol & Embryol, 140 Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China. (1)
Clinic of Reproductive Medicine, Department of Farm Animals Vetsuisse-Faculty University Zurich (1)
Clinic of Reproductive Medicine, Vetsuisse Faculty, University of Zurich (1)
Plate-forme d'Analyse Intégrative des Biomolécules et de Phénomique des Animaux d'Intérêt Bio-agronomique (PAIB2) UMR INRA 85 - CNRS 7247 - UFR - IFCE Physiologie de la Reproduction et des Comportements INRA Centre Val de Loire (Tours) 37380 NOUZILLY (1)
Institute of Molecular Biology (IMB) (1)

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Bovine adult versus prepubertal cumulus cells

The present study was undertaken to discover molecular markers in bovine cumulus cells predictive of oocyte competence and elucidate their functional significance. Differences in RNA transcript abundance in cumulus cells harvested from oocytes of adult versus prepubertal animals (model of poor oocy...

ORGANISM(S): Bos taurus

2010-05-25 | E-GEOD-10819 | biostudies-arrayexpress

Resolvin E1 in follicular fluid acts as a potential biomarker and improves oocyte developmental competence by optimizing cumulus cells

The metabolic profile of follicular fluid (FF) has been investigated to look for biomarkers for oocyte quality. Resolvin E1 (RvE1), a potent pro-resolving mediator, was reported to have protective action in cell function. The study aimed to examine the predictive value of RvE1 for oocyte quality ...

2020-03-26 | MTBLS1488 | MetaboLights

Contribution of CBX4 to cumulus oophorus cell phenotype in mice, and attendant effects in cumulus cell cloned embryos

Cumulus oophorus cells play an essential role in oocyte development. CBX4 is a member of the Polycomb complex, which plays a role in regulating cellular differentiation. We used siRNA mediated knockdown of Cbx4 expression followed by Affymetrix array analysis to evaluate the role of CBX4 in cumulus ...

ORGANISM(S): Mus musculus

2014-04-29 | E-GEOD-46565 | biostudies-arrayexpress

Transcription profiling of mouse cumulus cells from Bmp15-/- and Bmp15-/-Gdf9+/--DM animals

Mouse oocytes control cumulus cell metabolic processes that are deficient in the oocytes themselves and this delegation is necessary for oocyte development. Oocyte-derived bone morphogenetic factor 15 (BMP15) and growth differentiation factor 9 (GDF9) appear to be key regulators of follicular devel...

ORGANISM(S): Mus musculus

2008-06-15 | E-GEOD-7225 | biostudies-arrayexpress

Comparison of transcriptomes of mouse cumulus cells collected from mice before and after 6-h of hCG priming.

We sought to identify genes that are regulated by the ovulatory signals in mouse cumulus cells. We compared the transcriptomes between cumulus cells colected from mice before (hCG-0h) and after 6 h (hCG-6h) of hCG injection. 3 individual cumulus cell samples of hCG-0h and hCG-6h were collected and s...

ORGANISM(S): Mus musculus

2016-08-01 | E-GEOD-80255 | biostudies-arrayexpress

Expression data from cumulus cells from C57Bl/6 and Ptger2 (EP2) KO mice

To understand the role of prostaglandin (PG) receptor EP2 (Ptger2) signaling in ovulation and fertilization, we investigated time-dependent expression profiles in wild-type (WT) and Ptger2-/- cumuli before and after ovulation by using microarrays. We used Affymetrix U74A ver2 microarrays to investig...

ORGANISM(S): Mus musculus

2010-03-02 | E-GEOD-20439 | biostudies-arrayexpress

Extensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome

The elaboration of a quality oocyte is integrally linked to the correct developmental progression of cumulus cell phenotype. In humans and non-human primates, oocyte quality is diminished with in vitro maturation. To determine the changes in gene expression in rhesus monkey cumulus cells (CC) that o...

ORGANISM(S): Macaca mulatta

2011-05-22 | E-GEOD-25288 | biostudies-arrayexpress

Small RNA profiling of human cumulus cells and oocytes

Cumulus cells are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte maturation during follicular development. The bi-directional communication between the oocyte and the surrounding cumulus cells is crucial fo...

ORGANISM(S): Homo sapiens

2015-04-10 | E-GEOD-44792 | biostudies-arrayexpress

Rhesus monkey cumulus cells revert to a mural granulosa cell state following an ovulatory stimulus

Follicular somatic cells (mural granulosa cells and cumulus cells) and the oocyte communicate through paracrine interactions and through direct gap junctions between oocyte and cumulus cells. Considering that mural and cumulus cells arise through a common developmental pathway and that their differe...

ORGANISM(S): Macaca mulatta

2012-10-04 | E-GEOD-38387 | biostudies-arrayexpress

Transcription profiling of cumulus cell oocyte complexes isolated at different time points of ovulation to identify differentially expressed genes.

Cumulus-oocyte complexes were isolated at seperate time-points to generate temporal complexes. Targets from two biological replicates at each time point (0h, 8h, 16h post-hCG treatment) were generated and the expression profiles were determined using Affymetrix GeneChip Mouse Genome 430 2.0 Arrays....

ORGANISM(S): Mus musculus

2007-11-06 | E-GEOD-4260 | biostudies-arrayexpress

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