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TranscriptomicsNeonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates
Caesarean-delivered preterm pigs were fed 3 d of parenteral nutrition followed by 2 d of enteral formula feeding. Antibiotics (n=11) or control saline (n=13) were given twice daily from birth to tissue collection at d 5. NEC-lesions and intestinal structure, function, microbiology and immunity marke...
ORGANISM(S): Sus scrofa 
2013-08-21 | E-GEOD-48125 | biostudies-arrayexpress
TranscriptomicsIdentification of pathways and transcription factors relevant to gut inflammation and anti-inflammatory probiotics
Using Affymetrix data analysis, important signalling pathways and transcription factors relevant to gut inflammation and anti-inflammatory action of probiotics were identified using the clinically validated probiotic VSL#3 and the IL10-knockout mouse, an animal model for inflammatory bowel disease. ...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-13819 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of piglet ileal tissues to assess the impact of environment on microbial diversity and global transcriptional responses in the developing gut
The study investigated the impact of environment on the composition of the gut microbiota and mucosal immune development and function at gut surfaces in early and adult life. Piglets of similar genotype were reared in indoor and outdoor environments and in an experimental isolator facility. Mucosa-a...
ORGANISM(S): Sus scrofa 
2009-12-05 | E-GEOD-15256 | biostudies-arrayexpress
TranscriptomicsEffects of Bifidobacterium bifidum PRL2010 on gene expression in intestinal epithelial cells
Analysis of gene expression in Caco-2 intestinal epithelial cells stimulated with Bifidobacterium bifidum PRL2010. We used microarrays to investigate gene expression in intestinal epithelial cells in response to Bifidobacterium bifidum PRL2010, in particular genes involved in mucin pathways. Caco-2 ...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21976 | biostudies-arrayexpress
TranscriptomicsThe Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses
Microbiota-induced cytokine responses participate in gut homeostasis, but the cytokine balance at steady-state and the role of individual bacterial species in setting the balance remain elusive. Using gnotobiotic mouse models, we provide a systematic analysis of the role of microbiota in the inducti...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18056 | biostudies-arrayexpress
UnknownStereoacuity in children with anisometropic amblyopia.
Not available
S-EPMC3223370 | biostudies-literature
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