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TranscriptomicsGene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways
Keloids are benign tumors of the dermis that form during a protracted wound healing process. Susceptibility to keloid formation occurs predominantly in people of African and Asian descent. The key alteration(s) responsible for keloid formation has not been identified and there is no satisfactory t...
ORGANISM(S): Homo sapiens 
2007-11-26 | E-GEOD-7890 | biostudies-arrayexpress
TranscriptomicsGene expression profile of keloid tissue
Comparison of keloid to normal tissue One sample for each type of tissue examined
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-2945 | biostudies-arrayexpress
GenomicsIntegrated analysis of single-cell and spatial transcriptomics in keloids
Integrated analysis of single-cell and spatial transcriptomics in keloids
PRJNA751500 | ENA
UnknownRisk factors associated with the progression from keloids to severe keloids.
Not available
S-EPMC9276150 | biostudies-literature
GenomicsRevealing the Pathogenesis of Keloids Based on the Status: Active vs Inactive
Revealing the Pathogenesis of Keloids Based on the Status: Active vs Inactive
PRJNA909597 | ENA
TranscriptomicsIntegrated analysis of single-cell and spatial transcriptomics in keloids
To uncover the underlying pathophysiology of keloids, we used two technologies, single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST). we focused on the molecular signature of keloids. In this study, we provide the comprehensive transcriptomic atlas of keloids and its matched spati...
ORGANISM(S): Homo sapiens 
2022-01-21 | GSE181297 | GEO
GenomicsHypoxia and HIF-1α Regulate Collagen Production in Keloids
Hypoxia and HIF-1α Regulate Collagen Production in Keloids
PRJNA608004 | ENA
TranscriptomicsRevealing the Pathogenesis of Keloids Based on the Status: Active vs Inactive
Multiomics analysis demonstrated the distinct expression profile of active and inactive keloids. Clinically, these findings may provide the future appropriate directions for treatment of keloids depending on their activity and characteristics.
ORGANISM(S): Homo sapiens 
2023-06-01 | GSE220300 | GEO
UnknownKeloids: Current and emerging therapies.
Not available
S-EPMC7418256 | biostudies-literature
GenomicsTranscriptome network analysis of inflammation and fibrosis in keloids [mRNA-seq]
Transcriptome network analysis of inflammation and fibrosis in keloids [mRNA-seq]
PRJNA996551 | ENA
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