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TranscriptomicsGene expression analysis in mouse embryonic stem cells containing β-catenin lysine 49 to alanine mutation
β-Catenin is the major co-regulator of the Wnt signalling pathway. β-Catenin lysine 49 is post-translationally modified. The histone methyl transferase Ezh2 trimethylates β-catenin at lysine 49 and the acetyl transferase Cbp acetylates β-catenin at the same lysine. To determine the effects on g...
ORGANISM(S): Mus musculus 
2017-03-21 | E-MTAB-5523 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse embryonic stem cells
Analysis of the transcriptome of ß-catenin flox/- mES cells in comparison with ß-catenin null mES cells or ß-catenin null mES cells stably transfected with an E-cadherin-?-catenin fusion protein. Expression assay was performed using the Affymetrix GeneChip Mouse Gene 1.0 ST array. The experiment inc...
ORGANISM(S): Mus musculus 
2013-05-03 | E-GEOD-44543 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse conditional knock out of beta-catenin by K19-CRE at E7.5
expression profile of conditional knock out of beta-catenin by K19-CRE at E7.5. Tested a wild type with two alleles of beta-catenin, a heterzyote with one deleted allele and the conditional null in the domain on cytokeratin 19 driven CRE expression
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2519 | biostudies-arrayexpress
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