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TranscriptomicsHfq virulence regulation in enterohemorhagic Escherichia coli O157:H7 strain 86-24
Escherichia coli O157:H7 is a food-borne pathogen that causes bloody diarrhea and hemolytic uremic syndrome. Hfq is an sRNA chaperone protein that is involved in post-transcriptional regulation of virulence genes in pathogenic bacteria. In EHEC strain EDL933, Hfq acts a negative regulator of the loc...
ORGANISM(S): Escherichia coli O157:H7 
2012-01-06 | E-GEOD-30893 | biostudies-arrayexpress
UnknownAllosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.
Not available
S-EPMC3320953 | biostudies-literature
TranscriptomicsQseA regulation of virulence factors in EHEC
Enterohemorrhagic E. coli (EHEC) colonizes the large intestine and causes attaching and effacing lesions (AE). Most of the genes involved in the formation of AE lesions are encoded within a chromosomal pathogenicity island termed the Locus of Enterocyte Effacement (LEE). The LysR-like transcriptiona...
ORGANISM(S): Escherichia coli 
2010-09-07 | E-GEOD-18118 | biostudies-arrayexpress
TranscriptomicsMycobacterial cells have dual nickel-cobalt sensors: sequence-relationships and metal-sites of metal-responsive repressors are not congruent.
A novel ArsR-SmtB family transcriptional repressor, KmtR, has been characterised from mycobacteria. Mutants of M. tuberculosis lacking kmtR show elevated expression of Rv2025c encoding a deduced CDF-family metal-exporter. KmtR-dependent repression of the cdf and kmtR operator-promoters was alleviate...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-17 | E-BUGS-49 | biostudies-arrayexpress
UnknownPyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1.
Not available
S-EPMC5724760 | biostudies-literature
UnknownCharacterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1-Methyladenine and 3-Methylcytosine.
Not available
S-EPMC5709782 | biostudies-literature
UnknownProspective exploration of the effect of adiposity and associated microbial factors on healing and progression of diabetic foot ulcers in Tanzania: study protocol of a longitudinal cohort study.
Not available
S-EPMC6937068 | biostudies-literature
UnknownEnergetics of SecA dimerization.
Not available
S-EPMC3070768 | biostudies-literature
UnknownStructure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1).
Not available
S-EPMC3880629 | biostudies-literature
UnknownSynthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor.
Not available
S-EPMC4987248 | biostudies-literature
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