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In mammals, significant injury is generally followed by the formation of a fibrotic scar which provides structural integrity but fails to functionally restore damaged tissue. Spiny mice of the genus Acomys represent the first example of full skin autotomy in mammals. Acomys cahirinus h...
ORGANISM(S): Mus musculus (Mouse) Acomys cahirinus 
2025-10-31 | PXD047626 | Pride
Defining lncRNAs Associated with CHO Cell Growth and IgG Productivity by RNA-Seq I
Maintenance of the correct level and organization of nucleosomes is crucial for genome function. Here we uncover a role for a conserved bromodomain AAA-ATPase, Abo1, in maintenance of nucleosome architecture in fission yeast. Cells lacking abo1+ experience both a reduction and mis-positioning of nuc...
ORGANISM(S): Schizosaccharomyces pombe 
Antibody class switch recombination (CSR) in B lymphocytes joins two DNA double-strand breaks (DSBs) lying 100 to 200 kilobases (kb) apart within switch (S) regions in the immunoglobulin heavy chain locus (IgH). CSR-activated B lymphocytes generate multiple S-region DSBs in the donor Sm and in a do...
ORGANISM(S): Mus musculus 
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