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ProteomicsMass spectrometric detection of keratins in tear fluid
Keratin contamination is a common problem in mass spectrometry proteomic analyses, particularly in bottom-up mass spectrometry. The purpose of this study was to determine the protein contaminants introduced during the proteomic analysis of tear fluid.Human tear fluid samples were collected using Sch...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD061409 | Pride
Tear fluid Keratins Schirmer strip Mass spectrometry Proteomics Biomarkers 
UnknownInverted papilloma with Civatte/colloid body-like eosinophilic structures, accumulated with Keratins 14-, 6a-, 5-, and 4-like proteins in an oriental turtle dove (Streptopelia orientalis).
Not available
S-EPMC12604947 | biostudies-literature
UnknownNovel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells.
Not available
S-EPMC3204069 | biostudies-literature
UnknownKeratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex.
Not available
S-EPMC8624175 | biostudies-literature
TranscriptomicsKeratins control Nrf2 by regulating mitochondrial activity and barrier composition / Keratin-dependent TSLP expression suggests a link between skin blistering and atopic disease
The epidermal barrier protects the body against mechanical injury, infection and dehydration. The respective contribution of type I and type II keratins which form the major cytoskeleton in epidermal keratinocytes in barrier formation and stress protection is incompletely understood. Here, we reveal...
ORGANISM(S): Mus musculus 
2016-03-26 | E-GEOD-79590 | biostudies-arrayexpress
UnknownTranscript levels of keratin 1/5/6/14/15/16/17 as potential prognostic indicators in melanoma patients.
Not available
S-EPMC7806772 | biostudies-literature
UnknownFormation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.
Not available
S-EPMC37324 | biostudies-literature
TranscriptomicsFrizzled6 deficiency disrupts the differentiation process of nail development
Nails protect the soft tissue of the tips of digits in humans. In birds and mammals the equivalent claws are used for purposes including capturing prey, digging, climbing, fighting and maintaining dexterity and balance. The molecular mechanism of nail (and claw) development is largely unknown, but w...
ORGANISM(S): Mus musculus 
2013-09-13 | E-GEOD-40763 | biostudies-arrayexpress
UnknownDistribution of keratin subtypes in the thymus of Japanese black calves during acute thymic involution.
Not available
S-EPMC11830441 | biostudies-literature
ProteomicsEffects of 4-phenylbutyrate on human keratinocytes
Keratins 5 and 14 are critical for cytoskeletal integrity, as shown by missense mutations in these genes, which cause the severe skin fragility disorder epidermolysis bullosa simplex (EBS). The complexity of the pathomechanisms in EBS is not fully understood and no effective management exists. In ad...
ORGANISM(S): Homo sapiens (Human) 
2019-12-03 | PXD010028 | Pride
Epidermolysis bullosa Keratinocytes Skin Human Lc-ms/ms 
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