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TranscriptomicsMassively parallel single-cell RNA-Seq for dissecting cell type and cell state compositions
In multi-cellular organisms, biological function emerges when cells of heterogeneous types and states are combined into complex tissues. Nevertheless unbiased dissection of tissues into coherent cell subpopulations is currently lacking. We introduce an automated, massively parallel single cell RNA s...
ORGANISM(S): Mus musculus 
2014-02-14 | E-GEOD-54006 | biostudies-arrayexpress
TranscriptomicsHost microbiota constantly control maturation and function of microglia in the central nervous system (part 2)
As tissue macrophages of the central nervous system (CNS), microglia are critically involved in diseases of the CNS. However, it remains unknown what controls their maturation and activation under homeostatic conditions. Here we reveal significant contributions of the host microbiota to microglia ho...
ORGANISM(S): Mus musculus 
2015-05-25 | E-GEOD-67857 | biostudies-arrayexpress
TranscriptomicsHost microbiota constantly control maturation and function of microglia in the central nervous system (part 1)
As tissue macrophages of the central nervous system (CNS), microglia are critically involved in diseases of the CNS. However, it remains unknown what controls their maturation and activation under homeostatic conditions. Here we reveal significant contributions of the host microbiota to microglia ho...
ORGANISM(S): Mus musculus 
2015-05-25 | E-GEOD-62201 | biostudies-arrayexpress
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