Sort   by:  
 Page size 
TranscriptomicsAltered glycogen metabolism causes hepatomegaly following an Atg7 deletion
Autophagy is a lysosomal degradation process involved in the turnover of organelles or other cell constituents, in providing sources for energy production under starving conditions, and in cell metabolism. A key protein in the macroautophagic machinery is the autophagy related protein (Atg) 7. Const...
ORGANISM(S): Mus musculus 
2016-07-12 | E-MTAB-4389 | biostudies-arrayexpress
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
TranscriptomicsMLL2 facilitates long-range gene regulation through LINE1 elements [Micro-C]
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 deposition at bivalent promoters, which has been proposed to facilitate the induction of major develo...
ORGANISM(S): Mus musculus 
2025-10-23 | E-MTAB-15688 | biostudies-arrayexpress
GenomicsTranscriptional heterogeneity and lineage commitment in myeloid progenitors [ChIP-seq]
Within the bone marrow, hematopoietic stem cells differentiate and give rise to diverse blood cell types and functions. Currently, hematopoietic progenitors are defined using surface markers combined with functional assays that are not directly linked with the in vivo potential or gene regulatory me...
ORGANISM(S): Mus musculus 
2015-11-25 | E-GEOD-72858 | biostudies-arrayexpress
TranscriptomicsTranscriptional heterogeneity and lineage commitment in myeloid progenitors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-11-25 | E-GEOD-72859 | biostudies-arrayexpress
UnknownNutrient Intake and Its Association with Appendicular Total Lean Mass and Muscle Function and Strength in Older Adults: A Population-Based Study.
Not available
S-EPMC10892025 | biostudies-literature
GenomicsChromatin state dynamics during blood formation (ChIP-Seq)
We develop a new ChIpseq method (iChIP) to profile chromatin states of low cell number samples. We use IChIP to profile the chromatin dynamics during hematopoiesis across 16 different cell types which include the principal hematopoietic progenitors Examination of 2 different histone modifications in...
ORGANISM(S): Mus musculus 
2014-08-08 | E-GEOD-59636 | biostudies-arrayexpress
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
UnknownPrognosis and quality of life in patients with locally advanced rectal cancer after abdominoperineal resection in the CAO/ARO/AIO-04 randomized phase 3 trial.
Not available
S-EPMC11825916 | biostudies-literature
Sort   by:  
 Page size