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We used microarrays and a previously established linkage map to localize the genetic determinants of brain gene expression for a backcross family of lake whitefish species pairs (Coregonus sp.). Our goals were to elucidate the genomic distribution and sex-specificity of brain expression QTL (eQTL) ...
ORGANISM(S): Coregonus clupeaformis 
Mapping of expression quantitative trait loci (eQTL) is a powerful means for elucidating the genetic architecture of gene regulation. Yet, eQTL mapping has not been applied towards investigating the regulation architecture of genes involved in the process of population divergence, ultimately leading...
ORGANISM(S): Coregonus clupeaformis 
Long non-coding RNAs are frequently associated with broad modulation of gene expression and thus provide the cell with the ability to synchronize entire metabolic processes. We used transcriptomic and proteomic approaches to investigate whether the most abundant human cytomegalovirus-encoded lncRNA,...
ORGANISM(S): Human herpesvirus 5 strain Merlin Homo sapiens (Human) 
2021-07-27 | PXD022277 | Pride
The use of integrated approaches in genetic toxicology, including the incorporation of gene expression data to determine the molecular pathways involved in the response, is becoming more common. In a companion paper, a genomic biomarker was developed in human TK6 cells to classify chemicals as genot...
ORGANISM(S): Homo sapiens 
Genome-wide transcriptional profiling of cells subjected to a paraquat fulminant shock treatment (5mM for 10 minutes). Three independent biological materials were prepared for cells shock treated with paraquat and non-treated cells. A total 6 arrays which includes dye swap were analyzed.
ORGANISM(S): Bradyrhizobium japonicum USDA 110 
Genome-wide transcriptional profiling of cells exposed to 0.1 mM paraquat from time of inoculation. Three independent biological materials were prepared for cells exposed to 0.1 mM paraquat during growth and non-treated cells. A total 6 arrays which includes dye swap were analyzed.
ORGANISM(S): Bradyrhizobium japonicum USDA 110 
The use of integrated approaches in genetic toxicology, including the incorporation of gene expression data to determine the molecular pathways involved in the response, is becoming more common. In a companion paper, a genomic biomarker was developed in human TK6 cells to classify chemicals as genot...
ORGANISM(S): Homo sapiens 
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