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ProteomicsProteomic changes in aqueous humor of diabetic, age-related and post-vitrectomy cataract.
The focus of our research centers on exploring the proteome changes and corresponding signaling pathways involved in the development of diabetic cataract, age-related cataract and post-vitrectomy cataract, investigating aqueous humor, anterior capsule and lens human samples. Outstanding proteomic pr...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045554 | Pride
Keywords cataract Aqueous humor Aging Vitrectomy Diabetes Crystallin Cytoskeleton Proteomics 
UnknownXRCC1 and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
Not available
S-EPMC4384174 | biostudies-literature
UnknownCurrent Developments in Corneal Topography and Tomography.
Not available
S-EPMC8392046 | biostudies-literature
TranscriptomicsHSF4 microarray gene expression analysis in the newborn mouse lens.
Differential expression of HSF4 in null newborn mouse and wildtype lenses was examined to identify putative downstream targets of HSF4. To examine roles of Brg1 in mouse lens development, a dnBrg1 transgenic construct was expressed using the lens-specific aA-crystallin promoter in postmitotic lens f...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-22362 | biostudies-arrayexpress
UnknownRetropupillary Iris-Claw Intraocular Lenses: A Literature Review.
Not available
S-EPMC8240859 | biostudies-literature
UnknownA bibliometric advances in posterior capsule opacification.
Not available
S-EPMC12622752 | biostudies-literature
UnknownMapping of global research output in congenital cataracts from 1903 to 2021.
Not available
S-EPMC9191315 | biostudies-literature
TranscriptomicsStrain-specific Variation in Mouse Gene Expression and the Onset of Gap Junction Mutation-induced Cataracts
Disruption of the mouse gene encoding the gap junction subunit alpha3 connexin 46 (Cx46) results in the formation of lens cataracts. The timing of the onset of this lens opacity is affected by the genetic background, i.e. the mouse strain. To elucidate the mechanism by which cataracts form in the 12...
ORGANISM(S): Mus musculus 
2009-05-01 | GSE5645 | GEO
TranscriptomicsExpression Profiling of Retinal Detachment and Accelerated Re-attachment
Retinal detachment is a major cause of blindness due to penetrating trauma and ocular inflammation, and is often observed in many patients following cataract extraction surgery. When the retinal photoreceptors detach from their epithelium, stress signals and apoptotic pathways are initiated that wil...
ORGANISM(S): Mus musculus 
2007-11-10 | GSE5766 | GEO
TranscriptomicsComparison of apoptosis related gene expression in p7-p14 mouse lenses
Lens development exhibits a seamless progression from embryogenesis through ageing. Lens maturation and growth proceed throughout life; lens fibre cells differentiate from lens epithelial cells at the equator of the lens, migrate inwards at the bow region and mature around pre-existing fibre cells a...
ORGANISM(S): Mus musculus 
2007-08-11 | GSE8731 | GEO
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