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TranscriptomicsTranscription profiling of human leukemia cell lines KG-1, U937 and THP-1 vs. normal human blood monocytes
Methylation of CpG islands is associated with transcriptional repression and, in cancer, leads to the abnormal silencing of tumor-suppressor genes. Genome wide methylation profiling of myeloid leukemia cell lines identified a large number of genes with aberrantly methylated CpG islands. Comparative ...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3280 | biostudies-arrayexpress
GenomicsGenome wide ChIP-seq analysis of human TOP2B occupancy in KG-1 myeloid cell line
Genome wide ChIP-seq analysis of human TOP2B occupancy in KG-1 myeloid cell line
PRJNA462843 | ENA
TranscriptomicsThe Study of Gene Expression Profiles of KG-1 Cells Treated with Antrodia Camphorata Extracts using cDNA microarray.
Antrodia Camphorata is well known in Taiwan as a folk medicinal fungus with anticancer and anti-inflammatory effects. In this study, we used a human acute myelogenous leukemia cell line, KG-1, as the experimental model and constructed a high-throughput gene screen integrated platform by using a comb...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-3692 | biostudies-arrayexpress
MetabolomicsCell-intrinsic metabolic phenotypes identified in glioblastoma patients using mass spectrometry imaging of 13C-labeled glucose metabolism

Transcriptomic studies attempted to classify glioblastoma (GB) into subtypes that predict survival and that have different therapeutic vulnerabilities1-3. Here we identified three metabolic subtypes: glycolytic, oxidative and a mixed glycolytic/oxidative by mass spectrometry imaging of rapidly ex...

2025-05-08 | MTBLS12176 | MetaboLights
TranscriptomicsChIP-chip from KG-1 cells with HIV Tat
HIV-1 Tat can modulate the expression of both HIV and cellular genes. In antigen-presenting cells Tat induces the expression of a subset of interferon-stimulated genes (ISGs) in the absence of interferons (IFNs). We investigated the genome-wide Tat association with cellular promoters in immature den...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-GEOD-42191 | biostudies-arrayexpress
ProteomicsProteomics of exosomes derived from six human acute myeloid leukemia cell lines: KG-1a, KG-1, Kasumi-1, THP-1, U937, and HEL cells
This project includes 6 experimental groups (Group A-G) of exosomes derived from the human acute myeloid leukemia cell line KG-1a, KG-1, Kasumi-1, THP-1, U937, and HEL cells, resulting in a total of 6 Thermo RAW mass spectrometry files. LC-MS analysis was then used to identify and characterize prot...
ORGANISM(S): Homo Sapiens 
PXD079114 |
TranscriptomicsTranscription profiling of human leukemia cell lines treated with sera from Type I diabetes patients to investigate sera-induced transcriptional signatures.
Inflammation is common to many disorders and responsible for tissue and organ damage. However, the associated peripheral cytokine milieu is frequently dilute and difficult to measure, necessitating development of more sensitive and informative biomarkers for mechanistic studies, earlier diagnosis, a...
ORGANISM(S): Homo sapiens 
2010-09-16 | E-GEOD-24147 | biostudies-arrayexpress
GenomicsRNA-seq of decitabine-treated AML cell line panel
RNA-seq of decitabine-treated AML cell line panel
PRJNA923630 | ENA
GenomicsGenome wide ChIP-seq analysis of human TOP2B occupancy in KG-1 myeloid cell line
TOP2B is involved in transcriptional initiation in response to nuclear hormone ligands and plays a role in transcriptional elongation. Whole genome TOP2B ChIP-seq was carried out on human KG-1 cells in the presence and absence of the topoisomerase inhibitors mitoxantone and etoposide. Chromatin was ...
ORGANISM(S): Homo sapiens 
2020-06-30 | GSE114048 | GEO
TranscriptomicsMolecular profiling of myeloid leukemia cell lines
Cell lines. The myeloid cell lines CMK, HEL, HL-60, K-562, KASUMI-1, KG-1, LAMA-84, M-07e, MONO-MAC-1, MV4-11, NB-4, OCI-AML2, OCI-AML5, SIG-M5, THP-1, and UT-7 were obtained from the DSMZ in Braunschweig, Germany (http://www.dsmz.de). The cell line ME-1 was kindly provided by Dr. Ikuya Sakai, Ehim...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-8779 | biostudies-arrayexpress
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