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TranscriptomicsTranscriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting
This SuperSeries is composed of the following subset Series: GSE41241: Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [mRNA expression data] GSE41285: Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [CLIP-seq data...
ORGANISM(S): Mus musculus 
2012-11-09 | E-GEOD-41288 | biostudies-arrayexpress
TranscriptomicsTranscriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [mRNA expression data]
microRNAs (miRNAs) are essential components of gene regulation, but identification of miRNA targets remains a major challenge. Most target prediction and discovery relies on perfect complementarity of the miRNA seed to the 3’ untranslated region (UTR). However, it is unclear to what extent miRNAs ...
ORGANISM(S): Mus musculus 
2012-11-09 | E-GEOD-41241 | biostudies-arrayexpress
TranscriptomicsTranscriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [CLIP-seq data]
microRNAs (miRNAs) are essential components of gene regulation, but identification of miRNA targets remains a major challenge. Most target prediction and discovery relies on perfect complementarity of the miRNA seed to the 3’ untranslated region (UTR). However, it is unclear to what extent miRNAs ...
ORGANISM(S): Mus musculus 
2012-11-09 | E-GEOD-41285 | biostudies-arrayexpress
TranscriptomicsInferring transcriptional and microRNA-mediated regulatory programs in glioblastoma
Large-scale cancer genomics projects are profiling hundreds of tumors at multiple molecular layers, including copy number, mRNA and miRNA expression, but the mechanistic relationships between these layers are often excluded from computational models. We developed a supervised learning framework for...
ORGANISM(S): Homo sapiens 
2011-10-11 | E-GEOD-32876 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression differences between GT1, RH-ERP2009 and RH-JSR
Previous studies have shown that continuous in vitro passage can result in changes to the global gene expression profiles in mammalian cells. To examine the extent of gene expression differences between highly homologous type I strains, we took advantage of the T. gondii Affymetrix microarray conta...
ORGANISM(S): Toxoplasma gondii 
2010-06-20 | E-GEOD-16115 | biostudies-arrayexpress
GenomicsChIP-Seq analysis of PU.1, BATF, and JunB in murine BMDCs
Purpose: The purpose of this study is to identify the genome-wide binding sites for IRF4 interaction partners PU.1, BATF, and JunB in dendritic cells. These ChIP-seq data were integrated with gene expression analysis in IRF4-sufficient and -deficient BMDCs in order to assemble an IRF4 gene regulator...
ORGANISM(S): Mus musculus 
2013-12-22 | E-GEOD-52772 | biostudies-arrayexpress
UnknownEndorsement and phylogenetic analysis of some Fabaceae plants based on DNA barcoding.
Not available
S-EPMC9262781 | biostudies-literature
TranscriptomicsContext-dependent actions of Exendin-4 on β-cell function and dynamic changes in islet gene expression over time in vivo
GLP-1 analogues, such as exendin-4, preserve functional β-cell mass in various model systems and are revolutionising management of type 2 diabetes. Yet, comparatively little is known about effectiveness in the face of severe β-cell depletion. Moreover, direct and sequential effects of exendin-4 on...
ORGANISM(S): Mus musculus 
2014-04-11 | E-GEOD-37936 | biostudies-arrayexpress
UnknownPhytochemical Profiling, In Vitro and In Silico Anti-Microbial and Anti-Cancer Activity Evaluations and Staph GyraseB and h-TOP-IIβ Receptor-Docking Studies of Major Constituents of Zygophyllum coccineum L. Aqueous-Ethanolic Extract and Its Subsequent Fractions: An Approach to Validate Traditional Phytomedicinal Knowledge.
Not available
S-EPMC7866194 | biostudies-literature
UnknownFactors associated with an increase in tobacco use and alcohol drinking during the COVID-19 pandemic: A cross-sectional study of data from 105 countries.
Not available
S-EPMC9881585 | biostudies-literature
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