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UnknownEpigenetics insights from perceived facial aging.
Not available
S-EPMC10623707 | biostudies-literature
UnknownReconstructing repressor protein levels from expression of gene targets in Escherichia coli.
Not available
S-EPMC1693707 | biostudies-literature
TranscriptomicsEffects of soy supplementation on gene expression in breast cancer
Background There are conflicting reports on the impact of soy on breast carcinogenesis. This study examines the effects of soy supplementation on breast cancer-related genes and pathways. Methods Women (n = 140) with early-stage breast cancer were randomized to soy protein supplementation (n = ...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-58792 | biostudies-arrayexpress
GenomicsInduction of sarcomas by mutant IDH2
More than 50% of patients with chondrosarcomas exhibit gain-of-function mutations in either isocitrate dehydrogenase 1 (IDH1) or IDH2. In this study, we performed genome-wide CpG methylation sequencing of chondrosarcoma biopsies and found that IDH mutations were associated with DNA hypermethylation ...
ORGANISM(S): Homo sapiens 
2013-10-21 | E-GEOD-50539 | biostudies-arrayexpress
TranscriptomicsComprehensive evaluation of differential gene expression analysis methods for RNA-seq data
A large number of computational methods have been recently developed for analyzing differential gene expression (DE) in RNA-seq data. We report on a comprehensive evaluation of the commonly used DE methods using the SEQC benchmark data set and data from ENCODE project. We evaluated a number of key f...
ORGANISM(S): Homo sapiens 
2013-08-20 | E-GEOD-49712 | biostudies-arrayexpress
TranscriptomicsPatient glioma microarray for Impaired histone demethylation contributes to the cell differentiation arrest induced by cancer-associated isocitrate dehydrogenase mutation
To study the effects of IDH mutations, we collected and performed gene expression microarray analysis with tumor specimens from patients with grade II-III oligodendroglioma. Sequencing for mutations of IDH1 and IDH2 was done. Gene expression was compared between IDH wildtype vs. mutant samples
ORGANISM(S): Homo sapiens 
2012-02-01 | E-MEXP-3239 | biostudies-arrayexpress
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