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TranscriptomicsSingle-nucleus data for Uncovering the Molecular Logic of Cortical Wiring between Neuronal subtypes Across Development Through Ligand–Receptor Inference
The cerebral cortex comprises diverse excitatory and inhibitory neuron subtypes, each with distinct laminar positions and connectivity patterns. Yet, the molecular logic underlying their precise wiring remains poorly understood. To identify ligand–receptor (LR) interactions involved in cortical circ...
ORGANISM(S): Mus musculus 
2025-12-14 | E-MTAB-16355 | biostudies-arrayexpress
ProteomicsDeep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells
The mouse mpkCCD cell line is a continuous cultured epithelial cell line with characteristics of renal collecting duct principal cells. This line is widely used to study epithelial transport and its regulation. To provide a data resource useful for experimental design and interpretation in studies ...
ORGANISM(S): Mus musculus (Mouse) 
2015-10-06 | PXD002434 | Pride
Sds-page Kidney cortical collection duct Mass spectrometry Aquaporin-2 Differential centrifugation Lc-ms/ms 
TranscriptomicsRNA-seq of mouse primary cortical neurons transfected with a synthetic mimic of 5’tiRNA (Gly-GCC) or a scrambled control
tRNA-derived stress-induced RNAs (tiRNAs) are a new class of small non-coding RNA that have emerged as important regulators of cellular stress responses. tiRNAs are derived from specific tRNA cleavage by the stress-induced ribonuclease angiogenin (ANG). Loss-of-function mutations in the ANG gene are...
ORGANISM(S): Mus musculus 
2025-01-05 | E-MTAB-13537 | biostudies-arrayexpress
TranscriptomicsInterferon-related transcriptional program is induced by chronic hepatitis E infection in kidney-transplant recipients
Background: Hepatitis E Virus (HEV) is a new causative agent of chronic hepatitis in solid organ transplant recipients in Europe. Factors associated with the occurrence and persistence of chronic HEV infection remain largely unknown but chronic evolution seems to be the consequence of hostM-bM-^@M-^...
ORGANISM(S): Homo sapiens 
2013-01-29 | E-GEOD-36539 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses to injury in kidney cortex of nitric oxide depleted rats are ameliorated by vitamin E
Male Sprague-Dawley rats were given NOS inhibitor L-NNA (500 mg/l water) for 4 days, 21 days or 21 days with Vitamin E in chow (0.7 g/kg BW/day) (4d-LNNA, 21d-LNNA and 21d-LNNA+VitE, respectively).
ORGANISM(S): Rattus norvegicus 
2007-03-01 | E-UMCU-18 | biostudies-arrayexpress
GenomicsMus musculus
Early dexamethasone-inducible genes in M-1 Cortical Collecting Cells
PRJNA92397 | ENA
TranscriptomicsCell-type and subcellular compartment specific isolation of miRNAs directly from the mouse brain by in vivo AGO-APP
We derived two transgenic mouse lines expressing a T6B peptide either in the whole cytoplasm or targeted at the post-synapse, in order to perform AGO-APP directly from mouse tissues. We used these mice first to compare the expression of AGO-bound micro-RNAs in 2 types of neuron, the olfactory bulb i...
ORGANISM(S): Mus musculus 
2025-06-01 | E-MTAB-15124 | biostudies-arrayexpress
TranscriptomicsSpecified Bacterial Species in Gingival Crevicular Fluid Predict Diversity of Unattached Subgingival Microbiota
Analysis of gingival crevicular fluid (GCF) samples may give information of the identity of unattached (planktonic) subgingival bacteria, the 35 forefront candidates for systemic dispersal via ulcerated periodontal pocket epithelium. Our study represents the first one targeting the identity of bact...
ORGANISM(S): Homo sapiens 
2010-05-21 | E-GEOD-21929 | biostudies-arrayexpress
TranscriptomicsOral Samples (HOMIM-v.02); A Characterization of the Oral Microbiome in Allogeneic Stem Cell Transplant Patients
The purpose of this study is to describe the effects of allogeneic stem cell transplant on oral microbiota and to examine differences in those patients who acquired respiratory complications. Forty-five patients were consented for the study and followed for 100 days post-transplant. Eleven patients ...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-34439 | biostudies-arrayexpress
TranscriptomicsThe lifespan and kinetics of human Dendritic Cell subsets and their precursors in health and inflammation
To probe the phenotype of the cDC compartment during pathology, we developed a simplified human experimental skin blister model to sample infiltrating cells in order to examine the function and kinetics of DC populations in response to a bacterial insult in healthy individuals. ASDC were recruited t...
ORGANISM(S): Homo sapiens 
2024-09-24 | E-MTAB-14451 | biostudies-arrayexpress
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