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ProteomicsMechanisms preserving insulin action during high dietary fat intake in healthy men
Prolonged intervention studies investigating molecular metabolism are necessary for a deeper understanding of dietary effects on health. Here we provide mechanistic information about metabolic adaptation to fat-rich diets. Healthy men ingested saturated (SFA) or poly unsaturated (PUFA) fat-rich di...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-10-11 | PXD010516 | Pride
High fat diet 
ProteomicsProtein-restricted diet increases circulating FGF21 levels and necessitating an increase in energy intake to maintain body weight in healthy human individuals
Dietary protein restriction has been shown to increase energy expenditure and to improve insulin sensitivity in mice, but it is unknown whether humans exhibit similar phenotype to a prolonged eucaloric protein-restricted diet that meet daily protein minimum requirements. We hypothesize that a protei...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-04-22 | PXD047177 | Pride
Human Energy intake Body weight Healthy Fgf21 
ProteomicsThe exercise-regulated skeletal muscle phosphoproteome
Four healthy male volunteers (age: 24 - 27; BMI: 24.2 - 25.9 kg/m2) underwent a single bout of high-intensity bicycle exercise reaching a VO2 max approximately 95% with blood samples and muscle biopsies taken immediately pre- and post-exercise. Subjects reached 95% VO2 max in approximately 9 to 12 m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080777 | MassIVE
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