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MetabolomicsGregarines impact consumption and development but not glucosinolate metabolism in the mustard leaf beetle

Gregarines are usually classified as parasites, but recent studies suggest that they should be viewed on a parasitism-mutualism spectrum and may even be seen as part of the gut microbiota of host insects. As such, they may also impact the consumption of their hosts and/or be involved in the diges...

2025-07-10 | MTBLS9816 | MetaboLights
UnknownPooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma.
Not available
S-EPMC5089162 | biostudies-literature
MetabolomicsUnveiling molecular changes in guabiju during Aspergillus brasiliensis cultivation: insights from untargeted metabolomics

Black aspergilli exhibit remarkable bioconversion potential by transforming plant matrices into bioactive compounds, although their metabolic processes remain underexplored. This study investigated the biotransformation of metabolites during the solid-state cultivation of guabiju (Myrcianthes...

2025-08-08 | MTBLS12436 | MetaboLights
MetabolomicsHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
During tumor growth-when nutrient and anabolic demands are high-autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras-driven tumors additionally invoke non-autonomous autophagy in the microenvironment to support tumor growth, in part through ...
2021-09-24 | MTBLS2771 | MetaboLights
TranscriptomicsSuppression of Lung Adenocarcinoma Progression by Nkx2-1
Despite the high prevalence and poor outcome of patients with metastatic lung cancer, the mechanisms of tumour progression and metastasis remain largely uncharacterized. We modelled human lung adenocarcinoma, which frequently harbours activating point mutations in KRAS1 and inactivation of the p53-p...
ORGANISM(S): Mus musculus 
2011-01-27 | E-GEOD-26874 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse small intestine from PlagL2-/- animals reveals transcription factor PlagL2 regulates steps in chylomicron metabolism
Enterocytes assemble dietary lipids into chylomicron particles that are taken up by intestinal lacteal vessels and peripheral tissues. Although chylomicrons are known to assemble in part within membrane secretory pathways, the modifications required for efficient vascular uptake are unknown. We repo...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9123 | biostudies-arrayexpress
TranscriptomicsDe novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function
Background: Despite significant improvements in short-term kidney transplant survival, comparable increases in 5 and 10-year outcomes have not been achieved. Chronic allograft nephropathy (CAN) is a major cause of late graft loss. Toxic nephropathy and inadequate long-term immunosuppression are poss...
ORGANISM(S): Homo sapiens 
2004-09-23 | E-GEOD-1743 | biostudies-arrayexpress
no omics definedSingle cell RNA sequencing mapping the adult human esophagus in vivo and in vitro
Despite advances and innovations in characterization of adult esophageal epithelial stem cells, there is still a gap in reliable in vitro methods that closely recapitulate human cell behavior in a physiological-in vivo relevant fashion. Therefore, in this data set we set up to bench mark a detailed ...
ORGANISM(S): Homo sapiens 
2022-10-20 | E-MTAB-12266 | biostudies-arrayexpress
UnknownStructural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition.
Not available
S-EPMC8585918 | biostudies-literature
UnknownEarly short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis.
Not available
S-EPMC9112652 | biostudies-literature
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