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Many bacteria colonize surfaces and transition to a sessile mode of growth. The plant pathogen Agrobacterium tumefaciens produces a unipolar polysaccharide (UPP) adhesin at single cell poles that contact surfaces. Here we report that elevated levels of the intracellular signal cyclic diguanosine mon...
ORGANISM(S): Agrobacterium tumefaciens 
Targeted LC/MS Metabolomics. Cecal contents were lyophilized overnight and approximately 2.5-5 mg was homogenized in 250 µL of 50% acidified acetonitrile (0.3% formic acid) for targeted LC/MS/MS metabolomics (acylcarnitines, amino acids, organic acids, nucleotides, and CoAs) according to validated, ...
2026-06-19 | MTBLS14783 | MetaboLights

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
Data from ProteomeXchange, PXD ID: PXD001416. File: PBMC_1_con_cyt1-4.mgf. Published as part of J Proteome Res. 2014 Oct 27 . From the Abstract: {{i}} Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations indu...
ORGANISM(S): Homo_sapiens_viruses, Human 
ABSTRACT: Condensin is a central regulator of mitotic genome structure, with mutants showing poorly condensed chromosomes and profound segregation defects. Here we identify the fission yeast NCT complex, comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), Casein Kinase II (CKII) ...
ORGANISM(S): Schizosaccharomyces pombe 
TMPRSS2 is an androgen-regulated cell surface serine protease expressed predominantly in prostate epithelium. TMPRSS2 is expressed highly in localized high-grade prostate cancers and in the majority of human prostate cancer metastasis. Through the generation of mouse models with a targeted deletion ...
ORGANISM(S): Mus musculus 
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